{"id":426,"date":"2026-06-19T11:11:12","date_gmt":"2026-06-19T11:11:12","guid":{"rendered":"https:\/\/peptidesdivas.com\/?post_type=product&#038;p=426"},"modified":"2026-07-20T08:28:10","modified_gmt":"2026-07-20T08:28:10","slug":"kpv-research-peptide","status":"publish","type":"product","link":"https:\/\/peptidesdivas.com\/cs\/product\/kpv-research-peptide\/","title":{"rendered":"KPV"},"content":{"rendered":"<h1>KPV \u2013 Melanocortin-Derived Tripeptide for Research<\/h1>\n<p>KPV is a compact synthetic tripeptide composed of the amino acids lysine, proline and valine. It corresponds to the C-terminal three-amino-acid sequence of alpha-melanocyte-stimulating hormone, also known as \u03b1-MSH 11\u201313.<\/p>\n<p>Its short and clearly defined molecular structure makes KPV particularly relevant for professional laboratory research involving melanocortin-derived peptide biology, epithelial-cell signalling, cytokine-associated pathways, peptide transport and short-peptide characterisation.<\/p>\n<p>KPV is supplied as a lyophilised research material in a securely sealed vial with clear batch-specific product information and professional packaging.<\/p>\n<h2>Kl\u00ed\u010dov\u00e9 vlastnosti produktu<\/h2>\n<ul>\n<li>Synthetic tripeptide research material<\/li>\n<li>Composed of lysine, proline and valine<\/li>\n<li>Derived from the C-terminal region of \u03b1-MSH<\/li>\n<li>Also identified as \u03b1-MSH 11\u201313<\/li>\n<li>Compact and clearly defined peptide structure<\/li>\n<li>Relevant for epithelial and cytokine-signalling research<\/li>\n<li>Suitable for PepT1 transporter studies<\/li>\n<li>Useful for short-peptide characterisation<\/li>\n<li>Securely packaged research vial<\/li>\n<li>Rychl\u00e9 a sledovateln\u00e9 doru\u010den\u00ed do Evropy<\/li>\n<\/ul>\n<h2>What Is KPV?<\/h2>\n<p>KPV is the three-amino-acid sequence Lys\u2013Pro\u2013Val. It represents the C-terminal fragment of the naturally occurring peptide hormone \u03b1-MSH.<\/p>\n<p>Although KPV is derived from \u03b1-MSH, it is a much smaller research peptide with its own distinctive analytical and experimental profile. Its compact structure allows researchers to examine the activity of a minimal peptide sequence separately from the complete parent hormone.<\/p>\n<p>KPV has been investigated primarily in preclinical research models involving epithelial cells, immune-cell signalling and inflammatory-response pathways.<\/p>\n<h2>Melanocortin-Derived Peptide Research<\/h2>\n<p>Alpha-melanocyte-stimulating hormone belongs to the melanocortin peptide family. Different regions of the \u03b1-MSH sequence are studied for their distinct receptor and signalling properties.<\/p>\n<p>KPV may be relevant for research examining:<\/p>\n<ul>\n<li>\u03b1-MSH-derived peptide fragments<\/li>\n<li>C-terminal peptide activity<\/li>\n<li>Melanocortin-associated biology<\/li>\n<li>Minimal active peptide sequences<\/li>\n<li>Peptide-fragment comparison<\/li>\n<li>Vztahy mezi strukturou a aktivitou<\/li>\n<li>Receptor-dependent and receptor-independent signalling<\/li>\n<li>Short-peptide stability<\/li>\n<li>Cellular uptake mechanisms<\/li>\n<li>Comparative tripeptide analysis<\/li>\n<\/ul>\n<p>Research indicates that the biological profile of KPV may differ from that of full-length \u03b1-MSH and may not depend exclusively on classical melanocortin-receptor activation.<\/p>\n<h2>Epithelial-Cell Research<\/h2>\n<p>KPV has attracted scientific interest in experimental models involving intestinal and skin epithelial cells.<\/p>\n<p>Potential laboratory research areas include:<\/p>\n<ul>\n<li>Epithelial-cell signalling<\/li>\n<li>Cellular barrier models<\/li>\n<li>Intestinal epithelial research<\/li>\n<li>Modely keratinocyt\u016f<\/li>\n<li>Bun\u011b\u010dn\u00e9 stresov\u00e9 reakce<\/li>\n<li>Cytokine-stimulated cell models<\/li>\n<li>Epithelial peptide transport<\/li>\n<li>Cell\u2013peptide interactions<\/li>\n<li>Comparative cellular assays<\/li>\n<li>Short-peptide uptake studies<\/li>\n<\/ul>\n<p>These research areas are based mainly on in-vitro and preclinical findings and should not be interpreted as established clinical effects.<\/p>\n<h2>PepT1 Transporter Research<\/h2>\n<p>PepT1 is a membrane transporter involved in the cellular uptake of dipeptides and tripeptides.<\/p>\n<p>Laboratory research has investigated KPV as a possible PepT1 substrate in intestinal epithelial and immune-cell models. This creates opportunities for studying how peptide size, sequence and transporter expression influence cellular uptake.<\/p>\n<p>Relevant research topics include:<\/p>\n<ul>\n<li>Peptide-transporter interactions<\/li>\n<li>PepT1-mediated cellular uptake<\/li>\n<li>Intestinal peptide transport<\/li>\n<li>Transporter-expression models<\/li>\n<li>Concentration-dependent uptake<\/li>\n<li>Cellular peptide availability<\/li>\n<li>Intracellular peptide signalling<\/li>\n<li>Comparative substrate transport<\/li>\n<li>Epithelial transport mechanisms<\/li>\n<li>Peptide-delivery research<\/li>\n<\/ul>\n<p>Published studies have examined PepT1-mediated KPV uptake in cultured intestinal epithelial cells and murine intestinal models.<\/p>\n<h2>Cytokine and Cellular-Signalling Research<\/h2>\n<p>KPV is studied in experimental systems involving cytokine-stimulated cells and intracellular signalling pathways.<\/p>\n<p>Potential research areas include:<\/p>\n<ul>\n<li>Cytokine-associated signalling<\/li>\n<li>NF-\u03baB-related laboratory models<\/li>\n<li>IL-1\u03b2-associated pathways<\/li>\n<li>Cellular-response modulation<\/li>\n<li>Immune-cell signalling<\/li>\n<li>Epithelial stress models<\/li>\n<li>Transcription-factor activity<\/li>\n<li>Signal-transduction research<\/li>\n<li>Comparative peptide activity<\/li>\n<li>Cell-based assay development<\/li>\n<\/ul>\n<p>The precise molecular mechanisms associated with KPV remain an active area of research and may vary according to the cell type, transporter expression and experimental model.<\/p>\n<h2>Intestinal Research Models<\/h2>\n<p>Several preclinical studies have investigated KPV in intestinal epithelial and murine colitis models.<\/p>\n<p>These research environments may examine:<\/p>\n<ul>\n<li>Intestinal epithelial signalling<\/li>\n<li>Mucosal cell responses<\/li>\n<li>Cytokine-stimulated intestinal cells<\/li>\n<li>PepT1 transporter activity<\/li>\n<li>Cellular barrier models<\/li>\n<li>Immune\u2013epithelial communication<\/li>\n<li>Peptide uptake in intestinal tissue<\/li>\n<li>Comparative intestinal peptide research<\/li>\n<li>Formulation and delivery strategies<\/li>\n<\/ul>\n<p>These findings remain preclinical and do not establish that KPV can diagnose, prevent or treat intestinal disease in humans.<\/p>\n<h2>Skin and Keratinocyte Research<\/h2>\n<p>KPV has also been examined in experimental dermatological and keratinocyte models.<\/p>\n<p>Potential laboratory applications include:<\/p>\n<ul>\n<li>Keratinocyte signalling<\/li>\n<li>Epidermal cell models<\/li>\n<li>V\u00fdzkum ko\u017en\u00ed bari\u00e9ry<\/li>\n<li>Cytokine-stimulated keratinocytes<\/li>\n<li>Melanocortin-derived peptide comparison<\/li>\n<li>Bun\u011b\u010dn\u00e9 odpov\u011bdn\u00ed dr\u00e1hy<\/li>\n<li>Peptide penetration research<\/li>\n<li>Short-peptide formulation studies<\/li>\n<li>Srovn\u00e1vac\u00ed testy ko\u017en\u00edch bun\u011bk<\/li>\n<\/ul>\n<p>Research involving cultured keratinocytes has explored whether KPV-associated signalling differs from the classical cyclic-AMP response linked to full-length \u03b1-MSH.<\/p>\n<h2>Short-Peptide Research<\/h2>\n<p>Because KPV contains only three amino acids, it is particularly useful for research involving compact peptide structures.<\/p>\n<p>Relevant areas include:<\/p>\n<ul>\n<li>Tripeptide synthesis<\/li>\n<li>Peptide-sequence analysis<\/li>\n<li>Vztahy mezi strukturou a aktivitou<\/li>\n<li>Enzymatic stability<\/li>\n<li>Peptide degradation<\/li>\n<li>Transporter recognition<\/li>\n<li>Molekul\u00e1rn\u00ed modifikace<\/li>\n<li>Peptide-conjugate development<\/li>\n<li>Anal\u00fdza rozpustnosti<\/li>\n<li>V\u00fdvoj analytick\u00fdch metod<\/li>\n<li>Comparative short-peptide research<\/li>\n<\/ul>\n<p>Researchers may also compare KPV with full-length \u03b1-MSH, longer melanocortin fragments or structurally modified KPV analogues.<\/p>\n<h2>Aplikace analytick\u00e9ho v\u00fdzkumu<\/h2>\n<p>KPV may be suitable for analytical laboratory work involving:<\/p>\n<ul>\n<li>Vysoce v\u00fdkonn\u00e1 kapalinov\u00e1 chromatografie<\/li>\n<li>Kapalinov\u00e1 chromatografie s hmotnostn\u00ed spektrometri\u00ed<\/li>\n<li>Anal\u00fdza identity peptid\u016f<\/li>\n<li>Posouzen\u00ed \u010distoty<\/li>\n<li>Testov\u00e1n\u00ed stability<\/li>\n<li>Profilov\u00e1n\u00ed degradace<\/li>\n<li>V\u00fdzkum rozpustnosti<\/li>\n<li>Porovn\u00e1n\u00ed referen\u010dn\u00edch materi\u00e1l\u016f<\/li>\n<li>Kompatibilita s formulac\u00ed<\/li>\n<li>Analytical method validation<\/li>\n<li>Short-peptide characterisation<\/li>\n<\/ul>\n<p>The receiving laboratory is responsible for selecting and validating the appropriate solvents, concentrations and analytical procedures.<\/p>\n<h2>Specifikace produktu<\/h2>\n<table>\n<thead>\n<tr>\n<th>Charakteristika produktu<\/th>\n<th>Informace<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>N\u00e1zev produktu<\/td>\n<td>KPV<\/td>\n<\/tr>\n<tr>\n<td>Full sequence name<\/td>\n<td>Lysine\u2013Proline\u2013Valine<\/td>\n<\/tr>\n<tr>\n<td>Aminokyselinov\u00e1 sekvence<\/td>\n<td>Lys\u2013Pro\u2013Val<\/td>\n<\/tr>\n<tr>\n<td>Alternative designation<\/td>\n<td>\u03b1-MSH 11\u201313<\/td>\n<\/tr>\n<tr>\n<td>Kategorie produktu<\/td>\n<td>Syntetick\u00fd v\u00fdzkumn\u00fd peptid<\/td>\n<\/tr>\n<tr>\n<td>Typ peptidu<\/td>\n<td>Tripeptide<\/td>\n<\/tr>\n<tr>\n<td>D\u00e9lka peptidu<\/td>\n<td>T\u0159i aminokyseliny<\/td>\n<\/tr>\n<tr>\n<td>Parent peptide<\/td>\n<td>Alpha-melanocyte-stimulating hormone<\/td>\n<\/tr>\n<tr>\n<td>Formul\u00e1\u0159<\/td>\n<td>Lyofilizovan\u00fd v\u00fdzkumn\u00fd materi\u00e1l<\/td>\n<\/tr>\n<tr>\n<td>Prezentace<\/td>\n<td>Bezpe\u010dn\u011b uzav\u0159en\u00e1 v\u00fdzkumn\u00e1 lahvi\u010dka<\/td>\n<\/tr>\n<tr>\n<td>Dokumentace<\/td>\n<td>Analytick\u00e9 informace specifick\u00e9 pro danou \u0161ar\u017ei<\/td>\n<\/tr>\n<tr>\n<td>Obal<\/td>\n<td>Bezpe\u010dn\u00e9 a diskr\u00e9tn\u00ed balen\u00ed<\/td>\n<\/tr>\n<tr>\n<td>Zam\u00fd\u0161len\u00e9 pou\u017eit\u00ed<\/td>\n<td>V\u011bdeck\u00fd, analytick\u00fd a laboratorn\u00ed v\u00fdzkum<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Lyofilizovan\u00fd v\u00fdzkumn\u00fd form\u00e1t<\/h2>\n<p>KPV is supplied as a lyophilised research material in a securely sealed vial.<\/p>\n<p>Lyophilisation removes moisture and helps support product stability during controlled storage and transportation. Minor variations in physical appearance may occur because of production conditions, quantity and residual moisture.<\/p>\n<p>Product identity and analytical quality should always be assessed using the applicable batch documentation rather than physical appearance alone.<\/p>\n<h2>Kvalita a transparentnost produkt\u016f<\/h2>\n<p>Peptides Divas focuses on clear product specifications, careful handling and batch-level traceability.<\/p>\n<p>Available product documentation may include:<\/p>\n<ul>\n<li>Identifikace produktu<\/li>\n<li>Aminokyselinov\u00e1 sekvence<\/li>\n<li>\u010c\u00edslo \u0161ar\u017ee nebo \u0161ar\u017ee<\/li>\n<li>Uv\u00e1d\u011bn\u00e1 \u010distota<\/li>\n<li>HPLC anal\u00fdza<\/li>\n<li>Data hmotnostn\u00ed spektrometrie<\/li>\n<li>Informace o testov\u00e1n\u00ed<\/li>\n<li>Vzhled produktu<\/li>\n<li>Doporu\u010den\u00ed pro skladov\u00e1n\u00ed<\/li>\n<\/ul>\n<p>To poskytuje v\u00fdzkumn\u00edk\u016fm jasn\u00e9 a sledovateln\u00e9 informace o p\u0159\u00edslu\u0161n\u00e9 \u0161ar\u017ei produktu.<\/p>\n<h2>Informace o \u00falo\u017ei\u0161ti<\/h2>\n<p>Store KPV in its original sealed packaging under the conditions stated on the product label and applicable batch documentation.<\/p>\n<p>Protect the research material from:<\/p>\n<ul>\n<li>P\u0159\u00edm\u00e9 slune\u010dn\u00ed sv\u011btlo<\/li>\n<li>Nadm\u011brn\u00e9 teplo<\/li>\n<li>Vlhkost<\/li>\n<li>Kontaminace<\/li>\n<li>Po\u0161kozen\u00fd obal<\/li>\n<li>Opakovan\u00e9 teplotn\u00ed v\u00fdkyvy<\/li>\n<li>Zbyte\u010dn\u00e9 vystaven\u00ed vzduchu<\/li>\n<\/ul>\n<p>P\u0159ij\u00edmaj\u00edc\u00ed laborato\u0159 je zodpov\u011bdn\u00e1 za stanoven\u00ed vhodn\u00fdch postup\u016f p\u0159\u00edpravy, manipulace a skladov\u00e1n\u00ed pro sv\u016fj specifick\u00fd v\u00fdzkumn\u00fd protokol.<\/p>\n<h2>Why Choose KPV?<\/h2>\n<p>KPV provides a compact and clearly defined peptide structure for advanced cellular, analytical and transporter-related research.<\/p>\n<p>Key research advantages include:<\/p>\n<ul>\n<li>Simple three-amino-acid sequence<\/li>\n<li>Clear relationship to the \u03b1-MSH peptide family<\/li>\n<li>Relevant for epithelial-cell research<\/li>\n<li>Suitable for peptide-transporter studies<\/li>\n<li>Useful for cytokine-signalling models<\/li>\n<li>Valuable for short-peptide characterisation<\/li>\n<li>Convenient lyophilised format<\/li>\n<li>Jasn\u00e9 informace o produktu specifick\u00e9 pro danou \u0161ar\u017ei<\/li>\n<\/ul>\n<h2>Pro\u010d objedn\u00e1vat od Peptides Divas?<\/h2>\n<p>Peptides Divas combines carefully selected research products with fast and professional service.<\/p>\n<p>Customers benefit from:<\/p>\n<ul>\n<li>Jasn\u011b zobrazen\u00e9 specifikace produktu<\/li>\n<li>Analytick\u00e9 informace specifick\u00e9 pro danou \u0161ar\u017ei<\/li>\n<li>Rychl\u00e9 zpracov\u00e1n\u00ed objedn\u00e1vky<\/li>\n<li>Bezpe\u010dn\u00e9 a diskr\u00e9tn\u00ed balen\u00ed<\/li>\n<li>Mo\u017enosti sledovateln\u00e9 dopravy<\/li>\n<li>Pe\u010dliv\u00e9 zach\u00e1zen\u00ed s v\u00fdrobkem<\/li>\n<li>Responzivn\u00ed z\u00e1kaznick\u00e1 podpora<\/li>\n<li>Spolehliv\u00e9 evropsk\u00e9 doru\u010den\u00ed<\/li>\n<\/ul>\n<p>Choose KPV from Peptides Divas for advanced laboratory research involving melanocortin-derived peptide biology, epithelial signalling, peptide transport and short-peptide analysis.<\/p>\n<p>Pouze pro laboratorn\u00ed v\u00fdzkumn\u00e9 pou\u017eit\u00ed. Nen\u00ed ur\u010deno pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"<p class=\"isSelectedEnd\">KPV is a compact synthetic tripeptide composed of lysine, proline and valine. It corresponds to the C-terminal \u03b1-MSH 11\u201313 sequence and is studied in laboratory models involving epithelial signalling, cytokine-related pathways, peptide transport and short-peptide biology.<\/p>\n<p class=\"isSelectedEnd\">Its clearly defined three-amino-acid structure makes KPV particularly useful for analytical, comparative and cellular research.<\/p>\n<p>Supplied as a lyophilised research material with clear batch information, secure packaging and fast, trackable delivery.<\/p>","protected":false},"featured_media":418,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"nf_dc_page":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"product_brand":[],"product_cat":[34],"product_tag":[46],"class_list":["post-426","product","type-product","status-publish","has-post-thumbnail","product_cat-recovery-repair","product_tag-10-mg","first","instock","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.9 (Yoast SEO v28.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>KPV Research Peptide | Peptides Divas<\/title>\n<meta name=\"description\" content=\"Explore KPV, a melanocortin-derived tripeptide for advanced laboratory research involving epithelial signalling, 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