KPV is a compact synthetic tripeptide composed of the amino acids lysine, proline and valine. It corresponds to the C-terminal three-amino-acid sequence of alpha-melanocyte-stimulating hormone, also known as \u03b1-MSH 11\u201313.<\/p>\n
Its short and clearly defined molecular structure makes KPV particularly relevant for professional laboratory research involving melanocortin-derived peptide biology, epithelial-cell signalling, cytokine-associated pathways, peptide transport and short-peptide characterisation.<\/p>\n
KPV is supplied as a lyophilised research material in a securely sealed vial with clear batch-specific product information and professional packaging.<\/p>\n
KPV is the three-amino-acid sequence Lys\u2013Pro\u2013Val. It represents the C-terminal fragment of the naturally occurring peptide hormone \u03b1-MSH.<\/p>\n
Although KPV is derived from \u03b1-MSH, it is a much smaller research peptide with its own distinctive analytical and experimental profile. Its compact structure allows researchers to examine the activity of a minimal peptide sequence separately from the complete parent hormone.<\/p>\n
KPV has been investigated primarily in preclinical research models involving epithelial cells, immune-cell signalling and inflammatory-response pathways.<\/p>\n
Alpha-melanocyte-stimulating hormone belongs to the melanocortin peptide family. Different regions of the \u03b1-MSH sequence are studied for their distinct receptor and signalling properties.<\/p>\n
KPV may be relevant for research examining:<\/p>\n
Research indicates that the biological profile of KPV may differ from that of full-length \u03b1-MSH and may not depend exclusively on classical melanocortin-receptor activation.<\/p>\n
KPV has attracted scientific interest in experimental models involving intestinal and skin epithelial cells.<\/p>\n
Potential laboratory research areas include:<\/p>\n
These research areas are based mainly on in-vitro and preclinical findings and should not be interpreted as established clinical effects.<\/p>\n
PepT1 is a membrane transporter involved in the cellular uptake of dipeptides and tripeptides.<\/p>\n
Laboratory research has investigated KPV as a possible PepT1 substrate in intestinal epithelial and immune-cell models. This creates opportunities for studying how peptide size, sequence and transporter expression influence cellular uptake.<\/p>\n
Relevant research topics include:<\/p>\n
Published studies have examined PepT1-mediated KPV uptake in cultured intestinal epithelial cells and murine intestinal models.<\/p>\n
KPV is studied in experimental systems involving cytokine-stimulated cells and intracellular signalling pathways.<\/p>\n
Potential research areas include:<\/p>\n
The precise molecular mechanisms associated with KPV remain an active area of research and may vary according to the cell type, transporter expression and experimental model.<\/p>\n
Several preclinical studies have investigated KPV in intestinal epithelial and murine colitis models.<\/p>\n
These research environments may examine:<\/p>\n
These findings remain preclinical and do not establish that KPV can diagnose, prevent or treat intestinal disease in humans.<\/p>\n
KPV has also been examined in experimental dermatological and keratinocyte models.<\/p>\n
Potential laboratory applications include:<\/p>\n
Research involving cultured keratinocytes has explored whether KPV-associated signalling differs from the classical cyclic-AMP response linked to full-length \u03b1-MSH.<\/p>\n
Because KPV contains only three amino acids, it is particularly useful for research involving compact peptide structures.<\/p>\n
Relevant areas include:<\/p>\n
Researchers may also compare KPV with full-length \u03b1-MSH, longer melanocortin fragments or structurally modified KPV analogues.<\/p>\n
KPV may be suitable for analytical laboratory work involving:<\/p>\n
The receiving laboratory is responsible for selecting and validating the appropriate solvents, concentrations and analytical procedures.<\/p>\n
| Caratteristiche del prodotto<\/th>\n | Informazioni<\/th>\n<\/tr>\n<\/thead>\n |
|---|---|
| Nome del prodotto<\/td>\n | KPV<\/td>\n<\/tr>\n |
| Full sequence name<\/td>\n | Lysine\u2013Proline\u2013Valine<\/td>\n<\/tr>\n |
| Sequenza di amminoacidi<\/td>\n | Lys\u2013Pro\u2013Val<\/td>\n<\/tr>\n |
| Alternative designation<\/td>\n | \u03b1-MSH 11\u201313<\/td>\n<\/tr>\n |
| Categoria di prodotto<\/td>\n | Peptide sintetico per la ricerca<\/td>\n<\/tr>\n |
| Tipo di peptide<\/td>\n | Tripeptide<\/td>\n<\/tr>\n |
| lunghezza del peptide<\/td>\n | Tre amminoacidi<\/td>\n<\/tr>\n |
| Parent peptide<\/td>\n | Alpha-melanocyte-stimulating hormone<\/td>\n<\/tr>\n |
| Modulo<\/td>\n | Materiale di ricerca liofilizzato<\/td>\n<\/tr>\n |
| Presentazione<\/td>\n | Fiala da ricerca sigillata in modo sicuro<\/td>\n<\/tr>\n |
| Documentazione<\/td>\n | Informazioni analitiche specifiche per lotto<\/td>\n<\/tr>\n |
| Confezione<\/td>\n | Imballaggio sicuro e discreto<\/td>\n<\/tr>\n |
| Applicazione prevista<\/td>\n | Ricerca scientifica, analitica e di laboratorio<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\nFormato di ricerca liofilizzato<\/h2>\nKPV is supplied as a lyophilised research material in a securely sealed vial.<\/p>\n Lyophilisation removes moisture and helps support product stability during controlled storage and transportation. Minor variations in physical appearance may occur because of production conditions, quantity and residual moisture.<\/p>\n Product identity and analytical quality should always be assessed using the applicable batch documentation rather than physical appearance alone.<\/p>\n Qualit\u00e0 e trasparenza del prodotto<\/h2>\nPeptides Divas focuses on clear product specifications, careful handling and batch-level traceability.<\/p>\n Available product documentation may include:<\/p>\n
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