CJC-1295 with DAC – Long-Acting GHRH Analogue for Research

CJC-1295 with DAC is an advanced synthetic analogue of growth hormone-releasing hormone, commonly abbreviated as GHRH. Its specialised Drug Affinity Complex, or DAC, supports albumin binding and creates a longer-lasting molecular profile than native GHRH. This distinctive structure makes CJC-1295 particularly relevant for professional laboratory research involving GHRH receptor activity, pituitary signalling, the growth hormone and IGF-1 axis, peptide stability and long-acting molecular design. CJC-1295 is supplied as a premium lyophilised research material in a securely sealed vial, supported by clear batch information and professional packaging.

Key Product Features

• Advanced synthetic GHRH analogue
• Includes Drug Affinity Complex technology
• Designed to support albumin binding
• Long-acting molecular research profile
• Relevant for GHRH receptor studies
• Suitable for GH and IGF-1 pathway research
• Supplied as a lyophilised research material
• Clear batch-specific product information
• Secure and discreet packaging
• Fast and trackable delivery

What Is CJC-1295?

CJC-1295 is a modified peptide analogue based on the biologically active region of human growth hormone-releasing hormone. Natural GHRH is produced in the hypothalamus and communicates with receptors in the anterior pituitary. This signalling pathway is studied for its role in the synthesis and pulsatile release of growth hormone. Native GHRH has a short biological duration because it is rapidly broken down by enzymes. CJC-1295 was developed with selected amino-acid modifications and an additional DAC component to improve molecular stability and extend its research profile.

What Does DAC Mean?

DAC stands for Drug Affinity Complex. It is a specialised molecular modification designed to interact with circulating albumin. Albumin binding is widely studied in peptide development because it can:

• Reduce rapid enzymatic degradation
• Limit immediate molecular clearance
• Increase peptide stability
• Extend molecular exposure
• Support long-duration signalling research
• Improve the pharmacokinetic profile of peptide analogues

This albumin-binding design is the main difference between CJC-1295 with DAC and shorter-acting GHRH analogues that do not contain a DAC modification.

GHRH Receptor Research

CJC-1295 is studied primarily in relation to the growth hormone-releasing hormone receptor. The GHRH receptor is a G-protein-coupled receptor expressed on pituitary somatotroph cells. Receptor activation is associated with intracellular signalling pathways involved in growth hormone synthesis and release. Potential laboratory research areas include:

• GHRH receptor binding
• Receptor activation
• Ligand-receptor interactions
• Cyclic AMP signalling
• Pituitary cell communication
• Somatotroph cell activity
• Intracellular signal transduction
• Concentration-response relationships
• Receptor sensitivity
• Peptide-receptor pharmacology

Growth Hormone and IGF-1 Axis Research

CJC-1295 is frequently examined in experimental research involving the growth hormone and insulin-like growth factor 1 axis. This interconnected signalling system is relevant to studies examining:

• Pulsatile growth hormone signalling
• Pituitary hormone release
• IGF-1 pathway activity
• Endocrine feedback mechanisms
• Hypothalamic-pituitary communication
• Metabolic signalling
• Protein-turnover pathways
• Cellular growth signals
• Tissue-related signalling
• Hormone biomarker analysis

These areas represent fields of scientific investigation and do not imply an approved therapeutic application.

Long-Acting Peptide Design

The molecular design of CJC-1295 makes it particularly valuable for research into strategies that extend peptide stability. Relevant areas include:

• Albumin-binding technology
• Peptide conjugation
• Enzymatic resistance
• Molecular half-life extension
• Long-duration receptor activation
• Pharmacokinetic optimisation
• Peptide clearance mechanisms
• Structure-activity relationships
• Modified amino-acid sequences
• Long-acting peptide engineering

Researchers may compare CJC-1295 with native GHRH, shorter GHRH fragments or non-DAC analogues to investigate how molecular modifications affect stability and signalling behaviour.

Potential Research Applications

CJC-1295 may be relevant for controlled laboratory studies involving:

• Growth hormone-releasing hormone receptors
• Pituitary signalling pathways
• Growth hormone secretion models
• IGF-1-related signalling
• Endocrine feedback systems
• Pulsatile hormone-release patterns
• Peptide stability
• Albumin-binding mechanisms
• Molecular degradation
• Long-acting peptide development
• Comparative peptide pharmacology
• Analytical peptide characterisation
• Chromatographic analysis
• Mass-spectrometry analysis
• Biomarker research

The exact experimental design, concentrations, controls and analytical methods should be established by the qualified research institution conducting the study.

CJC-1295 with DAC Versus No DAC

CJC-1295 with DAC and products marketed as CJC-1295 No DAC should not be treated as identical compounds. CJC-1295 with DAC contains an albumin-binding modification designed to create a prolonged molecular profile. Products sold as CJC-1295 No DAC generally refer to a shorter-acting modified GHRH fragment commonly called Modified GRF (1–29).

Characteristic	CJC-1295 with DAC
Compound type	Modified GHRH analogue
DAC modification	Present
Albumin-binding design	Yes
Research profile	Long-acting
Primary research target	GHRH receptor
Main research pathway	Growth hormone and IGF-1 axis

Researchers should always verify the exact product identity and batch documentation before beginning an experiment.

Product Specifications

Product characteristic	Information
Product name	CJC-1295
Full product name	CJC-1295 with DAC
Product category	Synthetic research peptide
Compound type	Long-acting GHRH analogue
Molecular technology	Drug Affinity Complex
Primary research target	GHRH receptor
Research pathway	Growth hormone and IGF-1 axis
Form	Lyophilised powder
Presentation	Sealed research vial
Documentation	Batch-specific laboratory documentation
Packaging	Secure and discreet packaging
Intended application	Scientific and laboratory research

Lyophilised Research Format

CJC-1295 is supplied as a lyophilised research material in a securely sealed vial. Lyophilisation removes moisture and is commonly used to support peptide stability during controlled storage and transportation. Minor differences in appearance may occur because of production conditions, product quantity and residual moisture. Physical appearance alone should not be used to determine product identity or analytical quality. Researchers should review the applicable batch documentation before beginning laboratory work.

Quality and Transparency

Peptides Divas focuses on transparent product information, careful handling and batch-level traceability. Product documentation may include:

• Product identification
• Batch or lot number
• Reported purity
• HPLC analysis
• Mass-spectrometry data
• Testing information
• Storage recommendations
• Additional analytical observations

This gives researchers access to clear product information for the applicable batch.

Storage Information

Store the sealed CJC-1295 vial in a cool, dry and dark environment according to the product label and batch documentation. Protect the research material from:

• Direct sunlight
• Excessive heat
• Moisture
• Contamination
• Repeated temperature changes
• Unnecessary exposure to air

The receiving laboratory is responsible for establishing appropriate preparation, handling and storage procedures for its specific research protocol.

Why Choose CJC-1295?

CJC-1295 offers a distinctive long-acting molecular design for advanced GHRH-related research. Key advantages include:

• Specialised DAC albumin-binding technology
• Extended molecular research profile
• Clearly defined GHRH receptor pathway
• Relevant for GH and IGF-1 axis studies
• Suitable for peptide-stability research
• Valuable for comparative analogue research
• Convenient lyophilised presentation
• Clear batch-specific product information

Why Order from Peptides Divas?

Peptides Divas combines a carefully selected research catalogue with fast and professional service. Customers benefit from:

• Premium research materials
• Clear product specifications
• Batch-specific documentation
• Fast order processing
• Secure and discreet packaging
• Trackable shipping
• Responsive customer support
• Reliable European delivery

Choose CJC-1295 from Peptides Divas for advanced laboratory research involving GHRH receptor activity, pituitary signalling, peptide stability and the growth hormone and IGF-1 axis. For laboratory research use only. Not intended for human or veterinary use.