TB-500 – Thymosin Beta-4 Fragment for Research
TB-500 is a synthetic research peptide corresponding to the N-acetylated 17–23 fragment of human thymosin beta-4. Its compact seven-amino-acid sequence, Ac-LKKTETQ, represents an important region associated with actin-related cellular processes.
This clearly defined molecular structure makes TB-500 particularly relevant for professional laboratory studies involving actin dynamics, cytoskeletal organisation, endothelial-cell behaviour, cellular migration and peptide structure–activity relationships.
TB-500 is supplied as a premium lyophilised research material in a securely sealed vial with clear batch information, professional packaging and fast order processing from Peptides Divas.
Vigtige produktfunktioner
- Synthetic thymosin beta-4 fragment
- N-acetylated peptide sequence
- Clearly defined Ac-LKKTETQ structure
- Seven-amino-acid research peptide
- Relevant for actin-related cellular research
- Suitable for cytoskeletal and migration studies
- Useful for endothelial-cell models
- Suitable for analytical peptide characterisation
- Leveres som frysetørret forskningsmateriale
- Tydelige batchspecifikke produktoplysninger
- Sikker og diskret emballage
- Hurtig og sporbar levering i Europa
What Is TB-500?
TB-500 is a synthetic heptapeptide identified as the N-terminally acetylated 17–23 fragment of human thymosin beta-4.
Its amino-acid sequence is:
Ac-Leu–Lys–Lys–Thr–Glu–Thr–Gln
The abbreviated sequence is:
Ac-LKKTETQ
TB-500 contains the central actin-binding motif associated with thymosin beta-4, but it is a separate and much smaller research compound than full-length thymosin beta-4.
This distinction is important because TB-500 and complete thymosin beta-4 have different molecular sizes, analytical profiles and research characteristics.
TB-500 Versus Thymosin Beta-4
TB-500 is often incorrectly described as being identical to thymosin beta-4.
Full-length thymosin beta-4 is a naturally occurring 43-amino-acid protein involved in actin regulation. TB-500 is a synthetic seven-amino-acid fragment derived from one region of that protein.
| Produktkarakteristik |
TB-500 |
| Forbindelsestype |
Synthetic peptide fragment |
| Peptide sequence |
Ac-LKKTETQ |
| Peptidlængde |
Seven amino acids |
| Parent protein |
Thymosin beta-4 |
| Parent-protein region |
Amino acids 17–23 |
| Strukturelt træk |
N-terminal acetylation |
| Main research area |
Actin-related cellular signalling |
Researchers should confirm the exact sequence using the product label and batch-specific analytical documentation.
Actin-Related Research
Actin is an essential cellular protein involved in maintaining cell structure, movement and cytoskeletal organisation.
The LKKTETQ region is associated with the actin-binding domain of thymosin beta-4, making TB-500 relevant for research involving:
- Actin-related cellular processes
- Cytoskeletal organisation
- Cell shape and structural dynamics
- Actin polymerisation models
- Actin-binding interactions
- Cellular movement
- Focal adhesion pathways
- Cell-to-matrix communication
- Comparative actin-binding research
- Peptide–protein interactions
The exact behaviour of the isolated TB-500 fragment may differ from the activity of complete thymosin beta-4.
Cellular Migration Research
Cellular migration is a complex process involving actin remodelling, cytoskeletal organisation, adhesion proteins and extracellular signals.
TB-500 may be relevant for controlled laboratory research involving:
- Cellular migration
- Endothelial-cell movement
- Fibroblast migration
- Cytoskeletal rearrangement
- Cell adhesion
- Cell spreading
- Actin-dependent movement
- Concentration-response relationships
- Comparative peptide screening
- Migration-assay development
These research areas describe experimental cellular pathways and do not represent guaranteed biological or therapeutic outcomes.
Endothelial-Cell Research
Endothelial cells form the inner lining of blood vessels and are frequently used in laboratory research involving migration, adhesion and vascular signalling.
Potential TB-500 research applications include:
- Endothelial-cell migration
- Endothelial-cell adhesion
- Tubule-formation models
- Cell-sprouting assays
- Vascular signalling
- Angiogenesis-associated pathways
- Cytoskeletal organisation
- Cell–matrix interactions
- Comparative endothelial assays
- Molecular-response analysis
Research involving thymosin beta-4 and its actin-binding region has examined endothelial migration and vessel-sprouting mechanisms in preclinical models.
Cytoskeletal Research
The cytoskeleton is a dynamic network that supports cell shape, intracellular transport, movement and division.
TB-500 may be useful for studies examining:
- Actin-filament organisation
- Cytoskeletal remodelling
- Cellular polarity
- Cell-shape changes
- Intracellular transport
- Cell migration
- Adhesion-complex formation
- Mechanical cellular responses
- Actin-associated protein interactions
- Comparative cytoskeletal models
Its compact sequence offers researchers a convenient way to study a specific thymosin beta-4-derived region without using the entire parent protein.
Peptide Structure Research
The small and clearly defined structure of TB-500 makes it suitable for peptide chemistry and structure–activity research.
Potential research areas include:
- Synthetic heptapeptide characterisation
- N-terminal acetylation
- Peptidstabilitet
- Enzymatic degradation
- Peptide metabolite identification
- Struktur-aktivitetsforhold
- Amino-acid sequence analysis
- Molekylær modellering
- Peptide–protein interactions
- Comparative fragment research
Researchers may compare TB-500 with full-length thymosin beta-4, non-acetylated LKKTETQ or shorter metabolites to examine how molecular modifications affect analytical and cellular behaviour.
Metabolite Research
Analytical research has identified several shorter TB-500-related metabolites, including:
- Ac-LKKTE
- Ac-LKK
- Ac-LK
- Ac-L
These fragments may be studied in relation to:
- Peptidnedbrydning
- Metabolic stability
- Microsomal metabolism
- Fragment identification
- Analytical detection
- Comparative peptide activity
- Mass-spectrometry method development
- Time-dependent degradation
- Reference-standard analysis
Potentielle forskningsanvendelser
TB-500 may be relevant for controlled scientific studies involving:
- Actin-binding mechanisms
- Cytoskeletal organisation
- Cellular migration
- Cell adhesion
- Endothelial-cell models
- Fibroblast models
- Vascular signalling
- Angiogenesis-associated pathways
- Peptide-fragment biology
- N-terminal acetylation
- Struktur-aktivitetsforhold
- Peptidstabilitet
- Metabolite analysis
- Analytisk peptidkarakterisering
- Kromatografisk analyse
- Massespektrometrianalyse
- Comparative thymosin beta-4 research
De nøjagtige koncentrationer, kontroller og analytiske procedurer bør fastlægges af det kvalificerede laboratorium, der udfører forskningen.
Analytisk forskning
TB-500 is suitable for professional analytical applications involving:
- Højtydende væskekromatografi
- Væskekromatografi-massespektrometri
- Bekræftelse af peptididentitet
- Sequence verification
- Renhedsvurdering
- Stabilitetstestning
- Metabolite identification
- Nedbrydningsprofilering
- Opløselighedsvurdering
- Sammenligning af referencematerialer
- Udvikling af analytiske metoder
- Comparative peptide-fragment analysis
Because TB-500 is a short acetylated peptide, analytical procedures should be validated specifically for Ac-LKKTETQ.
Produktspecifikationer
| Produktkarakteristik |
Information |
| Produktnavn |
TB-500 |
| Full identification |
N-acetylated thymosin beta-4 fragment 17–23 |
| Peptide sequence |
Ac-LKKTETQ |
| Full sequence |
Ac-Leu–Lys–Lys–Thr–Glu–Thr–Gln |
| Produktkategori |
Syntetisk forskningspeptid |
| Peptidtype |
N-acetylated heptapeptide |
| Peptidlængde |
Seven amino acids |
| Parent protein |
Human thymosin beta-4 |
| Primary research areas |
Actin, cytoskeletal and cellular-migration research |
| Form |
Frysetørret forskningsmateriale |
| Præsentation |
Sikkert forseglet forskningsflaske |
| Dokumentation |
Batchspecifikke analytiske oplysninger |
| Emballage |
Sikker og diskret emballage |
| Tilsigtet anvendelse |
Videnskabelig, analytisk og laboratorieforskning |
Frysetørret forskningsformat
TB-500 is supplied as a lyophilised research material in a securely sealed vial.
Lyophilisation removes moisture and helps support peptide stability during controlled storage and transportation. Minor differences in physical appearance may occur because of quantity, production conditions and residual moisture.
Product identity, sequence and analytical quality should always be confirmed using the documentation associated with the applicable batch.
Kvalitet og produkttransparens
Peptides Divas focuses on clear product specifications, careful handling and batch-level traceability.
Available analytical information may include:
- Produktidentifikation
- Confirmed Ac-LKKTETQ sequence
- Batch- eller lotnummer
- Rapporteret renhed
- HPLC-analyse
- Massespektrometridata
- Testoplysninger
- Produktets udseende
- Opbevaringsanbefalinger
This provides researchers with clear and traceable product information for the applicable batch.
Opbevaringsoplysninger
Store TB-500 in its original sealed packaging according to the conditions stated on the product label and applicable batch documentation.
Protect the research material from:
- Direkte sollys
- Overdreven varme
- Fugtighed
- Forurening
- Beskadiget emballage
- Gentagne temperaturudsving
- Unødvendig eksponering for luft
The receiving laboratory is responsible for establishing appropriate preparation, handling and storage procedures for its specific research protocol.
Why Choose TB-500?
TB-500 provides a compact and clearly identified thymosin beta-4 fragment for advanced cellular and analytical research.
Key research advantages include:
- Precisely defined Ac-LKKTETQ sequence
- Compact seven-amino-acid structure
- Relevant for actin-related research
- Suitable for cellular-migration studies
- Useful for endothelial-cell models
- Valuable for peptide-metabolite analysis
- Suitable for structure–activity research
- Praktisk frysetørret præsentation
- Tydelige batchspecifikke produktoplysninger
Hvorfor bestille fra Peptides Divas?
Peptides Divas kombinerer omhyggeligt udvalgte forskningsmaterialer med hurtig, pålidelig og professionel service. Kunderne drager fordel af:
- Tydelig viste produktspecifikationer
- Batchspecifikke analytiske oplysninger
- Hurtig ordrebehandling
- Sikker og diskret emballage
- Sporbare forsendelsesmuligheder
- Omhyggelig beskyttelse af hætteglasset
- Responsiv kundesupport
- Pålidelig europæisk levering
Choose TB-500 from Peptides Divas for advanced laboratory research involving actin-related signalling, cellular migration, cytoskeletal organisation and peptide-fragment analysis.
For laboratory research use only. Not intended for human or veterinary use.
