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NAD+

34.95

NAD+ – Cellular Energy and Redox Research Compound

NAD+, short for nicotinamide adenine dinucleotide, is an essential cellular coenzyme studied for its central role in energy metabolism, redox reactions, mitochondrial activity and enzyme-dependent signalling pathways.

Its broad biochemical relevance makes NAD+ a valuable research compound for laboratories examining cellular respiration, metabolic regulation, electron transfer, oxidative stress, DNA-repair-associated pathways and NAD+-dependent enzyme activity.

Unlike peptide-based research materials, NAD+ is a naturally occurring dinucleotide coenzyme. It is supplied as a professional research material with clear product information, secure packaging and reliable order processing from Peptides Divas.

Klíčové vlastnosti produktu

  • Nicotinamide adenine dinucleotide in its oxidised form
  • Essential coenzyme in cellular redox reactions
  • Relevant for mitochondrial and metabolic research
  • Studied in relation to cellular energy production
  • Suitable for NAD+/NADH ratio studies
  • Relevant for sirtuin and PARP research
  • Useful for biochemical and enzymatic assays
  • Suitable for analytical characterisation
  • Securely packaged research material
  • Rychlé a sledovatelné doručení do Evropy

What Is NAD+?

NAD+ is the oxidised form of nicotinamide adenine dinucleotide, a coenzyme naturally present in cells.

The molecule consists of two nucleotides connected through phosphate groups. One nucleotide contains an adenine base, while the other contains nicotinamide.

NAD+ participates in numerous biochemical reactions by accepting electrons and hydrogen. During this process, NAD+ is converted into its reduced form, NADH.

The reversible conversion between NAD+ and NADH is fundamental to cellular redox balance and energy metabolism.

NAD+ and NADH

NAD+ and NADH represent two different redox states of the same coenzyme.

Charakteristický NAD+ NADH
Redox state Oxidised Reduced
Primary function Accepts electrons Carries and transfers electrons
Relevance výzkumu Metabolism and enzyme activity Respiration and electron transport
Relationship Converted into NADH Converted back into NAD+

The balance between NAD+ and NADH is frequently examined as an indicator of cellular redox status and metabolic activity.

Researchers may study how changes in the NAD+/NADH ratio influence:

  • Cellular respiration
  • Metabolic pathway activity
  • Mitochondrial function
  • Oxidative balance
  • Enzyme activity
  • Nutrient utilisation
  • Buněčné stresové reakce
  • Energy-substrate selection

Výzkum buněčné energie

NAD+ plays an important role in several pathways involved in converting nutrients into usable cellular energy.

Relevant metabolic processes include:

  • Glycolysis
  • The citric acid cycle
  • Oxidative phosphorylation
  • Oxidace mastných kyselin
  • Metabolismus aminokyselin
  • Mitochondrial electron transfer
  • Cellular respiration
  • ATP-related energy production

During these processes, NAD+ accepts electrons and is converted into NADH. NADH can subsequently transfer these electrons to the mitochondrial electron transport chain.

This makes NAD+ particularly relevant for laboratories examining the relationship between nutrient metabolism, mitochondrial respiration and cellular energy production.

Mitochondrial Research

Mitochondria rely on coordinated redox reactions to generate cellular energy. The availability and balance of NAD+ and NADH can influence mitochondrial metabolism and oxidative phosphorylation.

NAD+ may be used in laboratory research involving:

  • Mitochondrial respiration
  • Oxygen-consumption analysis
  • Electron-transport mechanisms
  • Oxidative phosphorylation
  • Mitochondrial enzyme activity
  • Metabolická flexibilita
  • Mitochondrial stress models
  • Cellular ATP-related pathways
  • Mitochondrial redox balance
  • Comparative metabolic analysis

Its established biochemical role makes NAD+ a useful reference compound for mitochondrial and cellular-energy research.

NAD+-Dependent Enzyme Research

In addition to its role in redox reactions, NAD+ serves as a substrate for several important enzyme families.

These include:

Sirtuins

Sirtuins are NAD+-dependent enzymes involved in protein deacylation and the regulation of metabolic, mitochondrial and gene-expression-related pathways.

Research involving sirtuins may examine:

  • NAD+-dependent deacetylation
  • Protein modification
  • Metabolic regulation
  • Mitochondrial signalling
  • Buněčné stresové reakce
  • Gene-expression pathways
  • Circadian signalling
  • Enzyme-substrate interactions

PARP Enzymes

Poly-ADP-ribose polymerases, commonly known as PARPs, use NAD+ as a substrate during ADP-ribosylation reactions.

PARP-related research may involve:

  • DNA-damage-response pathways
  • ADP-ribosylation
  • Chromatin-associated signalling
  • Cellular stress models
  • NAD+ consumption
  • Enzyme-activity analysis
  • Protein-modification pathways

CD38

CD38 is an NAD+-consuming enzyme associated with NAD+ metabolism and calcium-related cellular signalling.

Relevant research areas may include:

  • NAD+ degradation
  • Enzyme kinetics
  • Calcium-signalling pathways
  • Mobilní komunikace
  • NAD+ homeostasis
  • Comparative enzyme activity

Potenciální výzkumné aplikace

NAD+ may be relevant for controlled laboratory research involving:

  • Buněčný energetický metabolismus
  • NAD+/NADH redox balance
  • Mitochondrial respiration
  • Oxidative phosphorylation
  • Glycolytic pathways
  • Citric-acid-cycle activity
  • Oxidace mastných kyselin
  • Sirtuin enzyme activity
  • PARP-associated pathways
  • CD38-related metabolism
  • DNA-repair-associated signalling
  • Buněčné stresové reakce
  • Metabolic homeostasis
  • Enzyme kinetics
  • Biochemical assay development
  • Analytical method validation
  • Comparative coenzyme research
  • Stability and degradation analysis

These applications describe areas of scientific research and do not represent therapeutic or clinical claims.

NAD+ Biosynthesis and Metabolism

Cells can produce and recycle NAD+ through several biochemical pathways.

NAD+ metabolism may be studied in relation to:

  • The NAD+ salvage pathway
  • Nicotinamide recycling
  • Nicotinamide mononucleotide metabolism
  • Nicotinamide riboside metabolism
  • Tryptophan-derived biosynthesis
  • NAMPT enzyme activity
  • NMNAT enzyme activity
  • Cellular NAD+ consumption
  • Compartment-specific NAD+ pools
  • Metabolic homeostasis

NAD+ may therefore serve as a useful research reference when comparing NAD+ itself with related precursors such as NMN, NR and nicotinamide.

NAD+ Versus NAD+ Precursors

NAD+ should not be confused with compounds used by cells as precursors for NAD+ biosynthesis.

Sloučenina Research classification
NAD+ Oxidised dinucleotide coenzyme
NADH Reduced form of NAD+
NMN Nicotinamide mononucleotide precursor
NR Nicotinamide riboside precursor
Nicotinamide Vitamin B3-related salvage-pathway precursor

Each compound has different chemical, analytical and metabolic characteristics. Researchers should select the appropriate material for their specific experimental protocol.

Analytický výzkum

NAD+ may be used in analytical and biochemical method development involving:

  • Vysoce výkonná kapalinová chromatografie
  • Kapalinová chromatografie s hmotnostní spektrometrií
  • Spectrophotometric analysis
  • Enzymatic activity assays
  • Redox-state measurement
  • Testování stability
  • Degradation analysis
  • Reference-standard comparison
  • Metabolomic analysis
  • NAD+/NADH quantification
  • Biochemical assay validation

Because NAD+ can be affected by temperature, moisture, light and pH, laboratories should use analytical procedures specifically validated for the compound.

Specifikace produktu

Charakteristika produktu Informace
Název produktu NAD+
Celé jméno Nicotinamide Adenine Dinucleotide
Chemical form Oxidised NAD
Kategorie produktu Cellular coenzyme research compound
Related reduced form NADH
Primární oblasti výzkumu Energy metabolism, redox signalling and enzyme activity
Material format Laboratory research material
Prezentace Bezpečně uzavřená výzkumná lahvička
Dokumentace Informace o produktu specifické pro danou šarži
Obal Bezpečné a diskrétní balení
Zamýšlené použití Scientific, biochemical and analytical research

Informace o úložišti

Store NAD+ in its original sealed packaging according to the conditions stated on the product label and applicable batch documentation.

Protect the research material from:

  • Přímé sluneční světlo
  • Nadměrné teplo
  • Vlhkost
  • Kontaminace
  • Poškozený obal
  • Opakované teplotní výkyvy
  • Zbytečné vystavení vzduchu

NAD+ stability can depend on temperature, pH, concentration and preparation conditions. The receiving laboratory is responsible for establishing suitable storage and handling procedures for its research protocol.

Why Choose NAD+?

NAD+ offers a broad research profile for laboratories studying cellular energy, mitochondrial function and enzyme-dependent signalling.

Key research advantages include:

  • Central role in cellular redox chemistry
  • Relevance across multiple metabolic pathways
  • Suitable for mitochondrial research
  • Useful for NAD+/NADH balance studies
  • Relevant for sirtuin, PARP and CD38 research
  • Suitable for enzymatic and biochemical assays
  • Valuable for comparative metabolite analysis
  • Jasné informace o produktu a šarži

Proč objednávat od Peptides Divas?

Peptides Divas combines carefully selected research materials with fast, professional and reliable service.

Customers benefit from:

  • Jasně zobrazené specifikace produktu
  • Informace o produktu specifické pro danou šarži
  • Rychlé zpracování objednávky
  • Bezpečné a diskrétní balení
  • Možnosti sledovatelné dopravy
  • Pečlivé zacházení s výrobkem
  • Responzivní zákaznická podpora
  • Spolehlivé evropské doručení

Choose NAD+ from Peptides Divas for advanced laboratory research involving cellular energy metabolism, mitochondrial function, redox balance and NAD+-dependent enzyme activity.

Pouze pro laboratorní výzkumné použití. Není určeno pro humánní ani veterinární použití.

Využijte rychlé a spolehlivé zpracování objednávek od Peptides Divas.

  • Rychlé odeslání
  • Bezpečné a diskrétní balení
  • Sledovatelná zásilka
  • Pečlivá ochrana lahvičky
  • Spolehlivá evropská přeprava
  • Jasné informace o sledování po odeslání

Every NAD+ order is professionally packed to help keep the product sealed, protected and securely stored throughout delivery.

Kvalita, konzistence a transparentnost jsou v Peptides Divas důležité.

NAD+ is supplied with clear product and batch information to support reliable laboratory research and product traceability.

Dostupné analytické informace mohou zahrnovat:

  • Identifikace produktu
  • Číslo šarže nebo šarže
  • Uváděná čistota
  • HPLC analýza
  • Data hmotnostní spektrometrie
  • Informace o testování
  • Vzhled produktu
  • Doporučení pro skladování

Před zahájením výzkumu si prostudujte analytickou dokumentaci související s příslušnou šarží produktu.

NAD+ is supplied as a premium biochemical research compound for professional scientific, analytical and laboratory applications.

Its established biochemical profile makes it suitable for controlled research involving cellular metabolism, redox reactions, mitochondrial activity and NAD+-dependent enzymes.

Pouze pro laboratorní výzkumné použití. Není určeno pro humánní ani veterinární použití.

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