Melanotan II (MT2) – Cyclic Melanocortin Research Peptide

Melanotan II, commonly known as MT2 or MT-II, is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone, also known as α-MSH. Its compact cyclic structure and broad melanocortin-receptor activity make MT2 particularly relevant for advanced laboratory research involving melanocortin signalling, receptor pharmacology, pigmentation-related pathways, cellular communication and peptide structure–activity relationships. Melanotan II is supplied as a premium lyophilised research material in a securely sealed vial with clear batch information, professional packaging and fast delivery from Peptides Divas.

Caratteristiche principali del prodotto

• Synthetic cyclic heptapeptide
• Analogue of alpha-melanocyte-stimulating hormone
• Also known as Melanotan II, MT2 and MT-II
• Broad melanocortin-receptor research profile
• Relevant for MC1R-associated pigmentation research
• Suitable for receptor-binding and signalling studies
• Useful for cyclic-peptide characterisation
• Fornito come materiale di ricerca liofilizzato
• Informazioni chiare sul prodotto specifiche per lotto
• Imballaggio sicuro e discreto
• Spedizione europea rapida e tracciabile.

What Is Melanotan II?

Melanotan II is a laboratory-designed analogue of α-MSH, a naturally occurring peptide involved in melanocortin-receptor signalling. The molecule contains seven amino-acid components arranged in a compact cyclic structure. Cyclisation is achieved through a lactam bridge, helping create a more conformationally restricted molecule than the naturally occurring linear parent peptide. This specialised design makes MT2 useful for researchers examining how peptide cyclisation and modified amino-acid sequences influence receptor binding, molecular stability and biological signalling.

Alternative Product Names

Melanotan II may be identified by several common research names:

• Melanotan II
• Melanotan 2
• MT2
• MT-II
• Cyclic α-MSH analogue
• Melanocortin receptor agonist

Melanotan II should not be confused with Melanotan I. The two compounds have different molecular structures and research profiles.

Molecular Structure

Melanotan II is a cyclic heptapeptide based on the active central region of α-MSH. Important structural characteristics include:

• Seven-amino-acid peptide structure
• Cyclic lactam-bridged design
• Modified α-MSH-derived sequence
• Inclusion of non-standard amino-acid components
• Conformationally restricted molecular structure
• Broad melanocortin-receptor activity
• Distinct analytical profile compared with linear α-MSH

The cyclic design makes MT2 particularly relevant for structure–activity and peptide-engineering research.

Melanocortin-Receptor Research

Melanocortin receptors belong to the G-protein-coupled receptor family and are involved in multiple cellular and neuroendocrine signalling pathways. Melanotan II is studied as a non-selective agonist across multiple melanocortin receptor subtypes. Potential laboratory research areas include:

• Melanocortin-receptor binding
• Attivazione del recettore
• Interazioni ligando-recettore
• Segnalazione dell'AMP ciclico
• Trasduzione del segnale intracellulare
• Selettività del recettore
• Internalizzazione del recettore
• Relazioni concentrazione-risposta
• Comparative agonist pharmacology
• Relazioni struttura-attività

Its broad receptor profile makes MT2 useful as a reference compound in comparative melanocortin research.

MC1R and Pigmentation-Pathway Research

The melanocortin 1 receptor, commonly abbreviated as MC1R, is expressed by melanocytes and plays an important role in pigmentation biology. MT2 may be relevant for laboratory research involving:

• MC1R receptor activation
• Melanocyte signalling
• Melanin-production pathways
• Melanogenesis
• Pigment-cell biology
• Tyrosinase-associated pathways
• Melanosome formation
• Melanosome transfer
• Cellular pigmentation responses
• Comparative α-MSH analogue research

These applications describe laboratory research pathways and do not represent cosmetic or therapeutic claims.

Melanocyte Research

Melanocytes are specialised pigment-producing cells located in the skin, hair follicles and other tissues. Laboratory models involving MT2 may examine:

• Melanocyte receptor expression
• Cellular pigment production
• Melanin synthesis
• Cell-signalling responses
• Sensibilità del recettore
• Gene-expression changes
• Pigmentation-pathway activation
• Peptide concentration responses
• Comparative melanocyte assays
• Interactions between melanocytes and keratinocytes

Research outcomes can depend on the cell type, receptor expression, concentration, exposure period and experimental method used.

Neural Melanocortin Research

Certain melanocortin receptors are expressed within the central nervous system and are studied in relation to neuroendocrine communication and energy-balance pathways. MT2 has been used as a research tool in experimental models involving:

• Central melanocortin signalling
• MC3R- and MC4R-associated pathways
• Hypothalamic receptor activity
• Appetite-related signalling
• Satiety-related pathways
• Energy-balance models
• Autonomic communication
• Neural receptor pharmacology
• Behavioural research models
• Comparative central receptor studies

Findings from cell and animal models should not automatically be interpreted as established effects in humans.

Cyclic-Peptide Research

The cyclic structure of Melanotan II makes it particularly useful for peptide-design research. Potential applications include:

• Peptide cyclisation
• Lactam-bridge formation
• Conformational restriction
• Enzymatic stability
• Receptor-binding optimisation
• Modified amino-acid analysis
• Relazioni struttura-attività
• Molecular modelling
• Peptide degradation
• Comparative linear and cyclic peptide studies

Researchers may compare MT2 with natural α-MSH, Melanotan I or other melanocortin ligands to evaluate how structural changes affect receptor activity.

Potenziali applicazioni di ricerca

Melanotan II may be relevant for controlled scientific studies involving:

• Melanocortin receptor pharmacology
• MC1R-associated signalling
• Melanocyte biology
• Melanogenesis pathways
• Pigmentation-related cellular models
• MC3R and MC4R research
• Segnalazione neuroendocrina
• Energy-balance pathways
• GPCR activation
• Cyclic-peptide design
• Stabilità dei peptidi
• Relazioni struttura-attività
• Comparative α-MSH analogue studies
• Caratterizzazione analitica dei peptidi
• Analisi cromatografica
• Analisi mediante spettrometria di massa
• Test di stabilità e degradazione

The receiving laboratory is responsible for determining and validating suitable controls, concentrations and analytical procedures.

Melanotan I Versus Melanotan II

Melanotan I and Melanotan II are related α-MSH analogues but are not identical.

Caratteristica	Melanotan II
Nome alternativo	MT2 or MT-II
Tipo di peptide	Cyclic heptapeptide
Parent peptide	Alpha-melanocyte-stimulating hormone
Receptor profile	Broad melanocortin-receptor agonist
Progettazione molecolare	Lactam-bridged cyclic structure
Main research areas	Receptor pharmacology and pigmentation signalling

Always verify the exact product identity through the label and applicable batch documentation.

Specifiche del prodotto

Caratteristiche del prodotto	Informazioni
Nome del prodotto	Melanotan II
Common abbreviation	MT2 / MT-II
Categoria di prodotto	Peptide sintetico per la ricerca
Tipo composto	Cyclic α-MSH analogue
lunghezza del peptide	Seven amino-acid components
Caratteristica strutturale	Lactam-bridged cyclic structure
Obiettivi principali della ricerca	Melanocortin receptors
Main research areas	Receptor and pigmentation-pathway research
Modulo	Materiale di ricerca liofilizzato
Presentazione	Fiala da ricerca sigillata in modo sicuro
Documentazione	Informazioni analitiche specifiche per lotto
Confezione	Imballaggio sicuro e discreto
Applicazione prevista	Ricerca scientifica, analitica e di laboratorio

Formato di ricerca liofilizzato

Melanotan II is supplied as a lyophilised research material in a securely sealed vial. Lyophilisation removes moisture and helps support peptide stability during controlled storage and transport. Minor differences in physical appearance may occur because of product quantity, manufacturing conditions and residual moisture. Product identity, purity and analytical quality should be confirmed through the documentation associated with the applicable batch.

Qualità e trasparenza del prodotto

Peptides Divas focuses on clear product information, professional handling and batch-level traceability. Available analytical information may include:

• Identificazione del prodotto
• Peptide structure or sequence
• Numero di lotto
• Purezza dichiarata
• Analisi HPLC
• Dati di spettrometria di massa
• Informazioni sui test
• Aspetto del prodotto
• Consigli per la conservazione

Ciò fornisce ai ricercatori informazioni chiare e tracciabili relative al lotto di prodotto in questione.

Informazioni di archiviazione

Store Melanotan II in its original sealed packaging according to the conditions displayed on the product label and applicable batch documentation. Protect the research material from:

• Luce solare diretta
• Calore eccessivo
• Umidità
• Contaminazione
• Imballaggio danneggiato
• Fluttuazioni ripetute della temperatura
• Esposizione non necessaria all'aria

Il laboratorio ricevente è responsabile della definizione di procedure adeguate di manipolazione, preparazione e conservazione per il proprio specifico protocollo di ricerca.

Why Choose Melanotan II?

Melanotan II offers a distinctive cyclic molecular structure and broad melanocortin-receptor research profile. Key research advantages include:

• Clearly defined cyclic heptapeptide structure
• Direct relevance to melanocortin-receptor studies
• Suitable for MC1R-associated pathway research
• Useful for melanocyte and pigmentation models
• Valuable for cyclic-peptide analysis
• Relevant for structure–activity research
• Comoda confezione liofilizzata
• Informazioni chiare sul prodotto specifiche per lotto

Perché ordinare da Peptides Divas?

Peptides Divas combina materiali di ricerca accuratamente selezionati con un servizio rapido, affidabile e professionale. I clienti beneficiano di:

• Specifiche del prodotto chiaramente visualizzate
• Informazioni analitiche specifiche per lotto
• Elaborazione rapida degli ordini
• Imballaggio sicuro e discreto
• Opzioni di spedizione tracciabili
• Attenta protezione della fiala
• Assistenza clienti reattiva
• Consegna affidabile in Europa

Choose Melanotan II from Peptides Divas for advanced laboratory research involving melanocortin receptors, pigmentation-related signalling and cyclic-peptide pharmacology. For laboratory research use only. Not intended for human or veterinary use.