PT-141 (Bremelanotide) – Cyclic Melanocortin Research Peptide
PT-141, also known as Bremelanotide, is an advanced synthetic cyclic heptapeptide developed for professional laboratory research involving melanocortin receptor activity, central signalling pathways and cyclic peptide pharmacology.
Its compact molecular structure and broad melanocortin receptor profile make PT-141 particularly relevant for studies involving MC4R and MC1R activity, G-protein-coupled receptor signalling, neuroendocrine communication and peptide structure–activity relationships.
PT-141 is supplied as a premium lyophilised research material in a securely sealed vial with clear batch information, professional packaging and fast order processing from Peptides Divas.
Kluczowe cechy produktu
- Synthetic cyclic heptapeptide
- Also known as Bremelanotide and PT141
- Advanced melanocortin receptor agonist
- Relevant for MC4R and MC1R research
- Suitable for central melanocortin signalling studies
- Useful for GPCR pharmacology
- Relevant for cyclic peptide characterisation
- Dostarczany jako liofilizowany materiał badawczy
- Wyczyść informacje o produkcie specyficzne dla danej partii
- Bezpieczne i dyskretne opakowanie
- Szybka i śledzona dostawa na terenie Europy
What Is PT-141?
PT-141 is a synthetic melanocortin peptide with a conformationally restricted cyclic structure.
The molecule belongs to the melanocortin peptide family and is structurally related to alpha-melanocyte-stimulating hormone analogues. Its cyclic design helps create a stable and clearly defined molecular profile for receptor-binding and signalling research.
PT-141 is also known by its scientific name, Bremelanotide. The two names refer to the same active peptide compound.
Alternative Product Names
PT-141 may be identified under several names:
- PT-141
- PT141
- Bremelanotide
- Bremelanotide acetate
- Cyclic melanocortin peptide
- Melanocortin receptor agonist
Researchers should always confirm the exact chemical form and batch specifications using the product label and applicable analytical documentation.
Molecular Structure
Bremelanotide is a synthetic cyclic heptapeptide with an acetylated amino terminus and a free acid at the carboxyl terminus.
Its peptide structure is commonly represented as:
Ac-Nle-cyclo-(Asp–His–D-Phe–Arg–Trp–Lys–OH)
Important structural characteristics include:
- Seven-amino-acid cyclic peptide structure
- Lactam-bridged molecular design
- Acetylated amino terminus
- Free carboxyl terminus
- Modified amino-acid components
- Conformationally restricted structure
- Broad melanocortin receptor activity
- Distinct analytical profile
These characteristics make PT-141 particularly useful for cyclic peptide, receptor-binding and structure–activity research.
Melanocortin Receptor Research
PT-141 is studied as a non-selective agonist of several melanocortin receptor subtypes.
Relevant receptor systems include:
The relative activity of PT-141 differs between receptor subtypes, with MC1R and MC4R representing particularly important areas of scientific interest.
Potential research applications include:
- Melanocortin receptor binding
- Aktywacja receptora
- Interakcje ligand–receptor
- Sygnalizacja receptora sprzężonego z białkiem G
- Szlaki cyklicznego AMP
- Transdukcja sygnału wewnątrzkomórkowego
- Internalizacja receptora
- Odwrażliwienie receptora
- Relacje między koncentracją a reakcją
- Porównawcza farmakologia receptorów
MC4R and Central Signalling Research
The melanocortin 4 receptor, known as MC4R, is expressed in multiple regions of the central nervous system.
This makes PT-141 particularly relevant for research involving:
- Central melanocortin signalling
- Hypothalamic receptor activity
- Komunikacja neuroendokrynna
- Neural GPCR pathways
- Behaviour-related signalling models
- Autonomic communication
- Dopamine-associated research pathways
- Receptor-expression analysis
- Central ligand–receptor interactions
- Comparative MC4R agonist studies
PT-141 is frequently used as a research reference for examining how melanocortin receptor activation may influence centrally mediated signalling.
MC1R and Melanocyte Research
MC1R is strongly associated with melanocyte biology and pigmentation-related signalling.
PT-141 may therefore also be relevant for laboratory research involving:
- MC1R receptor activation
- Melanocyte signalling
- Melanin-expression pathways
- Pigmentation-related cellular models
- Selektywność receptora
- Comparative melanocortin ligands
- Cellular concentration responses
- Melanocyte gene expression
- GPCR signalling in pigment cells
- Receptor-mediated cellular communication
These applications describe laboratory research pathways and do not represent cosmetic claims.
Badania neuroendokrynne
Melanocortin receptors contribute to communication between the central nervous system and endocrine pathways.
Potential PT-141 research areas include:
- Sygnalizacja neuroendokrynna
- Hypothalamic pathway research
- Central receptor activation
- Neural transmitter interactions
- Hormone-associated signalling
- Behavioural response models
- Autonomic nervous system research
- Receptor-mediated cellular communication
- Comparative neuropeptide pharmacology
- Central nervous system peptide research
Experimental results can differ depending on the receptor subtype, cell type, concentration, administration model and analytical method.
Cyclic Peptide Research
The conformationally restricted structure of PT-141 makes it especially relevant for peptide design and molecular engineering.
Potential research topics include:
- Peptide cyclisation
- Lactam bridge formation
- Conformational restriction
- Stabilność molekularna
- Enzymatic degradation
- Receptor-binding optimisation
- Modified amino-acid analysis
- Farmakologia peptydów
- Relacje struktura–aktywność
- Comparative linear and cyclic peptides
- Molecular modelling
- Synthetic peptide chemistry
Researchers may compare PT-141 with Melanotan II, alpha-MSH or other melanocortin ligands to examine how small structural differences influence receptor activity.
PT-141 Versus Melanotan II
PT-141 and Melanotan II are closely related cyclic melanocortin peptides, but they should not be treated as identical compounds.
| Charakterystyczny |
PT-141 |
| Scientific name |
Bremelanotide |
| Typ peptydu |
Cyclic heptapeptide |
| C-terminal structure |
Free carboxylic acid |
| Main research profile |
Central melanocortin and receptor signalling |
| Important receptor targets |
MC4R and MC1R |
| Product identity |
Distinct from Melanotan II |
Researchers should always verify the exact compound identity before beginning laboratory analysis.
Potencjalne zastosowania badawcze
PT-141 may be relevant for controlled scientific research involving:
- Melanocortin receptor pharmacology
- MC4R receptor signalling
- MC1R receptor activity
- Central nervous system pathways
- Komunikacja neuroendokrynna
- GPCR activation
- Sygnalizacja cykliczna AMP
- Interakcje ligand–receptor
- Selektywność receptora
- Internalizacja receptora
- Peptide cyclisation
- Relacje struktura–aktywność
- Comparative melanocortin research
- Analityczna charakterystyka peptydów
- Analiza chromatograficzna
- Analiza metodą spektrometrii masowej
- Testowanie stabilności i degradacji
The exact experimental concentrations, controls and analytical procedures should be established by the qualified laboratory conducting the research.
Badania analityczne
PT-141 may be suitable for professional laboratory analysis involving:
- Chromatografia cieczowa wysokosprawna
- Chromatografia cieczowa-spektrometria mas
- Potwierdzenie tożsamości peptydu
- Molecular structure analysis
- Ocena czystości
- Testowanie stabilności
- Profilowanie degradacji
- Ocena rozpuszczalności
- Porównanie materiałów odniesienia
- Receptor-binding assays
- Zgodność formulacji
- Rozwój metod analitycznych
Product identity and analytical quality should always be evaluated using documentation associated with the applicable batch.
Specyfikacja produktu
| Charakterystyka produktu |
Informacja |
| Nazwa produktu |
PT-141 |
| Scientific name |
Bremelanotide |
| Alternative form |
Bremelanotide acetate |
| Kategoria produktu |
Syntetyczny peptyd badawczy |
| Typ złożony |
Cyclic melanocortin receptor agonist |
| Peptide structure |
Cyclic heptapeptide |
| Important research targets |
MC4R and MC1R |
| Główne obszary badań |
Melanocortin and neuroendocrine signalling |
| Formularz |
Liofilizowany materiał badawczy |
| Prezentacja |
Bezpiecznie zamknięta fiolka badawcza |
| Dokumentacja |
Informacje analityczne dotyczące konkretnej partii |
| Opakowanie |
Bezpieczne i dyskretne opakowanie |
| Przeznaczenie |
Badania naukowe, analityczne i laboratoryjne |
Format badań liofilizowanych
PT-141 is supplied as a lyophilised research material in a securely sealed vial.
Lyophilisation removes moisture and helps support peptide stability during controlled storage and transportation. Minor differences in physical appearance may occur due to product quantity, production conditions and residual moisture.
Physical appearance alone should not be used to confirm product identity, purity or concentration. Researchers should review the applicable batch documentation before beginning laboratory analysis.
Jakość i przejrzystość produktu
Peptides Divas focuses on clear product specifications, careful handling and batch-level traceability.
Available analytical information may include:
- Identyfikacja produktu
- Peptide structure
- Numer partii lub serii
- Zgłoszona czystość
- Analiza HPLC
- Dane spektrometrii masowej
- Informacje testowe
- Wygląd produktu
- Zalecenia dotyczące przechowywania
This provides researchers with clear and traceable product information for the applicable batch.
Informacje o przechowywaniu
Store PT-141 in its original sealed packaging under the conditions stated on the product label and applicable batch documentation.
Protect the research material from:
- Bezpośrednie światło słoneczne
- Nadmierne ciepło
- Wilgoć
- Zanieczyszczenie
- Uszkodzone opakowanie
- Powtarzające się wahania temperatury
- Niepotrzebna ekspozycja na powietrze
Laboratorium odbierające jest odpowiedzialne za ustalenie odpowiednich procedur przygotowywania, obsługi i przechowywania dla swojego konkretnego protokołu badawczego.
Why Choose PT-141?
PT-141 provides a distinctive cyclic molecular structure and broad melanocortin receptor research profile.
Key research advantages include:
- Clearly defined cyclic heptapeptide structure
- Direct relevance to MC4R research
- Suitable for central melanocortin signalling studies
- Useful for MC1R and melanocyte research
- Relevant for GPCR pharmacology
- Valuable for cyclic peptide analysis
- Suitable for structure–activity research
- Wygodna liofilizowana postać
- Wyczyść informacje o produkcie specyficzne dla danej partii
Dlaczego warto zamawiać w Peptides Divas?
Peptides Divas combines carefully selected research materials with fast, reliable and professional service.
Customers benefit from:
- Wyraźnie wyświetlane specyfikacje produktu
- Informacje analityczne dotyczące konkretnej partii
- Szybka realizacja zamówień
- Bezpieczne i dyskretne opakowanie
- Opcje śledzenia przesyłki
- Staranne zabezpieczenie fiolki
- Szybka i sprawna obsługa klienta
- Niezawodna dostawa do Europy
Choose PT-141 from Peptides Divas for advanced laboratory research involving melanocortin receptors, central signalling, neuroendocrine pathways and cyclic peptide pharmacology.
For laboratory research use only. Not intended for human or veterinary use.
