PT-141 (Bremelanotide) – Cyclic Melanocortin Research Peptide
PT-141, also known as Bremelanotide, is an advanced synthetic cyclic heptapeptide developed for professional laboratory research involving melanocortin receptor activity, central signalling pathways and cyclic peptide pharmacology.
Its compact molecular structure and broad melanocortin receptor profile make PT-141 particularly relevant for studies involving MC4R and MC1R activity, G-protein-coupled receptor signalling, neuroendocrine communication and peptide structure–activity relationships.
PT-141 is supplied as a premium lyophilised research material in a securely sealed vial with clear batch information, professional packaging and fast order processing from Peptides Divas.
Klíčové vlastnosti produktu
- Synthetic cyclic heptapeptide
- Also known as Bremelanotide and PT141
- Advanced melanocortin receptor agonist
- Relevant for MC4R and MC1R research
- Suitable for central melanocortin signalling studies
- Useful for GPCR pharmacology
- Relevant for cyclic peptide characterisation
- Dodává se jako lyofilizovaný výzkumný materiál
- Jasné informace o produktu specifické pro danou šarži
- Bezpečné a diskrétní balení
- Rychlé a sledovatelné doručení do Evropy
What Is PT-141?
PT-141 is a synthetic melanocortin peptide with a conformationally restricted cyclic structure.
The molecule belongs to the melanocortin peptide family and is structurally related to alpha-melanocyte-stimulating hormone analogues. Its cyclic design helps create a stable and clearly defined molecular profile for receptor-binding and signalling research.
PT-141 is also known by its scientific name, Bremelanotide. The two names refer to the same active peptide compound.
Alternative Product Names
PT-141 may be identified under several names:
- PT-141
- PT141
- Bremelanotide
- Bremelanotide acetate
- Cyclic melanocortin peptide
- Melanocortin receptor agonist
Researchers should always confirm the exact chemical form and batch specifications using the product label and applicable analytical documentation.
Molecular Structure
Bremelanotide is a synthetic cyclic heptapeptide with an acetylated amino terminus and a free acid at the carboxyl terminus.
Its peptide structure is commonly represented as:
Ac-Nle-cyclo-(Asp–His–D-Phe–Arg–Trp–Lys–OH)
Important structural characteristics include:
- Seven-amino-acid cyclic peptide structure
- Lactam-bridged molecular design
- Acetylated amino terminus
- Free carboxyl terminus
- Modified amino-acid components
- Conformationally restricted structure
- Broad melanocortin receptor activity
- Distinct analytical profile
These characteristics make PT-141 particularly useful for cyclic peptide, receptor-binding and structure–activity research.
Melanocortin Receptor Research
PT-141 is studied as a non-selective agonist of several melanocortin receptor subtypes.
Relevant receptor systems include:
The relative activity of PT-141 differs between receptor subtypes, with MC1R and MC4R representing particularly important areas of scientific interest.
Potential research applications include:
- Melanocortin receptor binding
- Aktivace receptoru
- Interakce ligand-receptor
- Signalizace receptoru spřaženého s G-proteinem
- Cyklické AMP dráhy
- Intracelulární signální transdukce
- Internalizace receptorů
- Desenzibilizace receptorů
- Vztahy mezi koncentrací a odezvou
- Srovnávací farmakologie receptorů
MC4R and Central Signalling Research
The melanocortin 4 receptor, known as MC4R, is expressed in multiple regions of the central nervous system.
This makes PT-141 particularly relevant for research involving:
- Central melanocortin signalling
- Hypothalamic receptor activity
- Neuroendokrinní komunikace
- Neural GPCR pathways
- Behaviour-related signalling models
- Autonomic communication
- Dopamine-associated research pathways
- Receptor-expression analysis
- Central ligand–receptor interactions
- Comparative MC4R agonist studies
PT-141 is frequently used as a research reference for examining how melanocortin receptor activation may influence centrally mediated signalling.
MC1R and Melanocyte Research
MC1R is strongly associated with melanocyte biology and pigmentation-related signalling.
PT-141 may therefore also be relevant for laboratory research involving:
- MC1R receptor activation
- Melanocyte signalling
- Melanin-expression pathways
- Pigmentation-related cellular models
- Selektivita receptoru
- Comparative melanocortin ligands
- Cellular concentration responses
- Melanocyte gene expression
- GPCR signalling in pigment cells
- Receptor-mediated cellular communication
These applications describe laboratory research pathways and do not represent cosmetic claims.
Neuroendokrinní výzkum
Melanocortin receptors contribute to communication between the central nervous system and endocrine pathways.
Potential PT-141 research areas include:
- Neuroendokrinní signalizace
- Hypothalamic pathway research
- Central receptor activation
- Neural transmitter interactions
- Hormone-associated signalling
- Behavioural response models
- Autonomic nervous system research
- Receptor-mediated cellular communication
- Comparative neuropeptide pharmacology
- Central nervous system peptide research
Experimental results can differ depending on the receptor subtype, cell type, concentration, administration model and analytical method.
Cyclic Peptide Research
The conformationally restricted structure of PT-141 makes it especially relevant for peptide design and molecular engineering.
Potential research topics include:
- Peptide cyclisation
- Lactam bridge formation
- Conformational restriction
- Molekulární stabilita
- Enzymatic degradation
- Receptor-binding optimisation
- Modified amino-acid analysis
- Farmakologie peptidů
- Vztahy mezi strukturou a aktivitou
- Comparative linear and cyclic peptides
- Molecular modelling
- Synthetic peptide chemistry
Researchers may compare PT-141 with Melanotan II, alpha-MSH or other melanocortin ligands to examine how small structural differences influence receptor activity.
PT-141 Versus Melanotan II
PT-141 and Melanotan II are closely related cyclic melanocortin peptides, but they should not be treated as identical compounds.
| Charakteristický |
PT-141 |
| Scientific name |
Bremelanotide |
| Typ peptidu |
Cyclic heptapeptide |
| C-terminal structure |
Free carboxylic acid |
| Main research profile |
Central melanocortin and receptor signalling |
| Important receptor targets |
MC4R and MC1R |
| Product identity |
Distinct from Melanotan II |
Researchers should always verify the exact compound identity before beginning laboratory analysis.
Potenciální výzkumné aplikace
PT-141 may be relevant for controlled scientific research involving:
- Melanocortin receptor pharmacology
- MC4R receptor signalling
- MC1R receptor activity
- Central nervous system pathways
- Neuroendokrinní komunikace
- GPCR activation
- Cyklická AMP signalizace
- Interakce ligand-receptor
- Selektivita receptoru
- Internalizace receptorů
- Peptide cyclisation
- Vztahy mezi strukturou a aktivitou
- Comparative melanocortin research
- Analytická charakterizace peptidů
- Chromatografická analýza
- Analýza hmotnostní spektrometrií
- Testování stability a degradace
The exact experimental concentrations, controls and analytical procedures should be established by the qualified laboratory conducting the research.
Analytický výzkum
PT-141 may be suitable for professional laboratory analysis involving:
- Vysoce výkonná kapalinová chromatografie
- Kapalinová chromatografie s hmotnostní spektrometrií
- Potvrzení identity peptidu
- Molecular structure analysis
- Posouzení čistoty
- Testování stability
- Profilování degradace
- Posouzení rozpustnosti
- Porovnání referenčních materiálů
- Receptor-binding assays
- Kompatibilita s formulací
- Vývoj analytických metod
Product identity and analytical quality should always be evaluated using documentation associated with the applicable batch.
Specifikace produktu
| Charakteristika produktu |
Informace |
| Název produktu |
PT-141 |
| Scientific name |
Bremelanotide |
| Alternative form |
Bremelanotide acetate |
| Kategorie produktu |
Syntetický výzkumný peptid |
| Typ sloučeniny |
Cyclic melanocortin receptor agonist |
| Peptide structure |
Cyclic heptapeptide |
| Important research targets |
MC4R and MC1R |
| Primární oblasti výzkumu |
Melanocortin and neuroendocrine signalling |
| Formulář |
Lyofilizovaný výzkumný materiál |
| Prezentace |
Bezpečně uzavřená výzkumná lahvička |
| Dokumentace |
Analytické informace specifické pro danou šarži |
| Obal |
Bezpečné a diskrétní balení |
| Zamýšlené použití |
Vědecký, analytický a laboratorní výzkum |
Lyofilizovaný výzkumný formát
PT-141 is supplied as a lyophilised research material in a securely sealed vial.
Lyophilisation removes moisture and helps support peptide stability during controlled storage and transportation. Minor differences in physical appearance may occur due to product quantity, production conditions and residual moisture.
Physical appearance alone should not be used to confirm product identity, purity or concentration. Researchers should review the applicable batch documentation before beginning laboratory analysis.
Kvalita a transparentnost produktů
Peptides Divas focuses on clear product specifications, careful handling and batch-level traceability.
Available analytical information may include:
- Identifikace produktu
- Peptide structure
- Číslo šarže nebo šarže
- Uváděná čistota
- HPLC analýza
- Data hmotnostní spektrometrie
- Informace o testování
- Vzhled produktu
- Doporučení pro skladování
This provides researchers with clear and traceable product information for the applicable batch.
Informace o úložišti
Store PT-141 in its original sealed packaging under the conditions stated on the product label and applicable batch documentation.
Protect the research material from:
- Přímé sluneční světlo
- Nadměrné teplo
- Vlhkost
- Kontaminace
- Poškozený obal
- Opakované teplotní výkyvy
- Zbytečné vystavení vzduchu
Přijímající laboratoř je zodpovědná za stanovení vhodných postupů přípravy, manipulace a skladování pro svůj specifický výzkumný protokol.
Why Choose PT-141?
PT-141 provides a distinctive cyclic molecular structure and broad melanocortin receptor research profile.
Key research advantages include:
- Clearly defined cyclic heptapeptide structure
- Direct relevance to MC4R research
- Suitable for central melanocortin signalling studies
- Useful for MC1R and melanocyte research
- Relevant for GPCR pharmacology
- Valuable for cyclic peptide analysis
- Suitable for structure–activity research
- Pohodlná lyofilizovaná prezentace
- Jasné informace o produktu specifické pro danou šarži
Proč objednávat od Peptides Divas?
Peptides Divas combines carefully selected research materials with fast, reliable and professional service.
Customers benefit from:
- Jasně zobrazené specifikace produktu
- Analytické informace specifické pro danou šarži
- Rychlé zpracování objednávky
- Bezpečné a diskrétní balení
- Možnosti sledovatelné dopravy
- Pečlivá ochrana lahvičky
- Responzivní zákaznická podpora
- Spolehlivé evropské doručení
Choose PT-141 from Peptides Divas for advanced laboratory research involving melanocortin receptors, central signalling, neuroendocrine pathways and cyclic peptide pharmacology.
For laboratory research use only. Not intended for human or veterinary use.
