PT-141 (Bremelanotide) – Cyclic Melanocortin Research Peptide
PT-141, also known as Bremelanotide, is an advanced synthetic cyclic heptapeptide developed for professional laboratory research involving melanocortin receptor activity, central signalling pathways and cyclic peptide pharmacology.
Its compact molecular structure and broad melanocortin receptor profile make PT-141 particularly relevant for studies involving MC4R and MC1R activity, G-protein-coupled receptor signalling, neuroendocrine communication and peptide structure–activity relationships.
PT-141 is supplied as a premium lyophilised research material in a securely sealed vial with clear batch information, professional packaging and fast order processing from Peptides Divas.
Viktiga produktfunktioner
- Syntetisk cyklisk heptapeptid
- Also known as Bremelanotide and PT141
- Advanced melanocortin receptor agonist
- Relevant for MC4R and MC1R research
- Suitable for central melanocortin signalling studies
- Användbar för GPCR-farmakologi
- Relevant for cyclic peptide characterisation
- Levereras som frystorkat forskningsmaterial
- Tydlig batchspecifik produktinformation
- Säker och diskret förpackning
- Snabb och spårbar leverans i Europa
What Is PT-141?
PT-141 is a synthetic melanocortin peptide with a conformationally restricted cyclic structure.
The molecule belongs to the melanocortin peptide family and is structurally related to alpha-melanocyte-stimulating hormone analogues. Its cyclic design helps create a stable and clearly defined molecular profile for receptor-binding and signalling research.
PT-141 is also known by its scientific name, Bremelanotide. The two names refer to the same active peptide compound.
Alternativa produktnamn
PT-141 may be identified under several names:
- PT-141
- PT141
- Bremelanotide
- Bremelanotide acetate
- Cyclic melanocortin peptide
- Melanokortinreceptoragonist
Researchers should always confirm the exact chemical form and batch specifications using the product label and applicable analytical documentation.
Molekylstruktur
Bremelanotide is a synthetic cyclic heptapeptide with an acetylated amino terminus and a free acid at the carboxyl terminus.
Its peptide structure is commonly represented as:
Ac-Nle-cyclo-(Asp–His–D-Phe–Arg–Trp–Lys–OH)
Important structural characteristics include:
- Seven-amino-acid cyclic peptide structure
- Lactam-bridged molecular design
- Acetylated amino terminus
- Free carboxyl terminus
- Modified amino-acid components
- Conformationally restricted structure
- Broad melanocortin receptor activity
- Distinct analytical profile
These characteristics make PT-141 particularly useful for cyclic peptide, receptor-binding and structure–activity research.
Melanocortin Receptor Research
PT-141 is studied as a non-selective agonist of several melanocortin receptor subtypes.
Relevant receptor systems include:
The relative activity of PT-141 differs between receptor subtypes, with MC1R and MC4R representing particularly important areas of scientific interest.
Potential research applications include:
- Melanocortin receptor binding
- Receptoraktivering
- Ligand-receptorinteraktioner
- G-proteinkopplad receptorsignalering
- Cykliska AMP-vägar
- Intracellulär signaltransduktion
- Receptorinternalisering
- Receptor-desensibilisering
- Koncentration-responsförhållanden
- Jämförande receptorfarmakologi
MC4R and Central Signalling Research
The melanocortin 4 receptor, known as MC4R, is expressed in multiple regions of the central nervous system.
This makes PT-141 particularly relevant for research involving:
- Central melanokortinsignalering
- Hypotalamisk receptoraktivitet
- Neuroendokrin kommunikation
- Neural GPCR pathways
- Behaviour-related signalling models
- Autonom kommunikation
- Dopamine-associated research pathways
- Receptoruttrycksanalys
- Central ligand–receptor interactions
- Comparative MC4R agonist studies
PT-141 is frequently used as a research reference for examining how melanocortin receptor activation may influence centrally mediated signalling.
MC1R and Melanocyte Research
MC1R is strongly associated with melanocyte biology and pigmentation-related signalling.
PT-141 may therefore also be relevant for laboratory research involving:
- MC1R-receptoraktivering
- Melanocytsignalering
- Melanin-expression pathways
- Pigmentrelaterade cellulära modeller
- Receptorselektivitet
- Comparative melanocortin ligands
- Cellular concentration responses
- Melanocyte gene expression
- GPCR signalling in pigment cells
- Receptor-mediated cellular communication
These applications describe laboratory research pathways and do not represent cosmetic claims.
Neuroendokrin forskning
Melanocortin receptors contribute to communication between the central nervous system and endocrine pathways.
Potential PT-141 research areas include:
- Neuroendokrin signalering
- Hypothalamic pathway research
- Central receptor activation
- Neural transmitter interactions
- Hormone-associated signalling
- Behavioural response models
- Autonomic nervous system research
- Receptor-mediated cellular communication
- Jämförande neuropeptidfarmakologi
- Central nervous system peptide research
Experimental results can differ depending on the receptor subtype, cell type, concentration, administration model and analytical method.
Cyclic Peptide Research
The conformationally restricted structure of PT-141 makes it especially relevant for peptide design and molecular engineering.
Potential research topics include:
- Peptidcyklisering
- Lactam bridge formation
- Konformationsbegränsning
- Molekylär stabilitet
- Enzymatisk nedbrytning
- Optimering av receptorbindning
- Modifierad aminosyraanalys
- Peptidfarmakologi
- Struktur-aktivitetsförhållanden
- Comparative linear and cyclic peptides
- Molekylär modellering
- Synthetic peptide chemistry
Researchers may compare PT-141 with Melanotan II, alpha-MSH or other melanocortin ligands to examine how small structural differences influence receptor activity.
PT-141 Versus Melanotan II
PT-141 and Melanotan II are closely related cyclic melanocortin peptides, but they should not be treated as identical compounds.
| Karakteristisk |
PT-141 |
| Vetenskapligt namn |
Bremelanotide |
| Peptidtyp |
Cyklisk heptapeptid |
| C-terminal structure |
Free carboxylic acid |
| Main research profile |
Central melanocortin and receptor signalling |
| Important receptor targets |
MC4R and MC1R |
| Produktidentitet |
Distinct from Melanotan II |
Researchers should always verify the exact compound identity before beginning laboratory analysis.
Potentiella forskningsapplikationer
PT-141 may be relevant for controlled scientific research involving:
- Melanokortinreceptorns farmakologi
- MC4R receptor signalling
- MC1R receptor activity
- Central nervous system pathways
- Neuroendokrin kommunikation
- GPCR-aktivering
- Cyklisk AMP-signalering
- Ligand-receptorinteraktioner
- Receptorselektivitet
- Receptorinternalisering
- Peptidcyklisering
- Struktur-aktivitetsförhållanden
- Comparative melanocortin research
- Analytisk peptidkarakterisering
- Kromatografisk analys
- Masspektrometrianalys
- Stabilitets- och nedbrytningstestning
De exakta experimentella koncentrationerna, kontrollerna och analysprocedurerna bör fastställas av det kvalificerade laboratoriet som utför forskningen.
Analytisk forskning
PT-141 may be suitable for professional laboratory analysis involving:
- Högpresterande vätskekromatografi
- Vätskekromatografi – masspektrometri
- Bekräftelse av peptididentitet
- Molecular structure analysis
- Renhetsbedömning
- Stabilitetstestning
- Nedbrytningsprofilering
- Löslighetsbedömning
- Jämförelse av referensmaterial
- Receptor-binding assays
- Formuleringskompatibilitet
- Analytisk metodutveckling
Product identity and analytical quality should always be evaluated using documentation associated with the applicable batch.
Produktspecifikationer
| Produktegenskaper |
Information |
| Produktnamn |
PT-141 |
| Vetenskapligt namn |
Bremelanotide |
| Alternative form |
Bremelanotide acetate |
| Produktkategori |
Syntetisk forskningspeptid |
| Förenad typ |
Cyclic melanocortin receptor agonist |
| Peptide structure |
Cyklisk heptapeptid |
| Important research targets |
MC4R and MC1R |
| Primära forskningsområden |
Melanocortin and neuroendocrine signalling |
| Form |
Frystorkat forskningsmaterial |
| Presentation |
Säkert förseglad forskningsflaska |
| Dokumentation |
Batchspecifik analytisk information |
| Förpackning |
Säker och diskret förpackning |
| Avsedd tillämpning |
Vetenskaplig, analytisk och laboratorieforskning |
Frystorkat forskningsformat
PT-141 is supplied as a lyophilised research material in a securely sealed vial.
Lyophilisation removes moisture and helps support peptide stability during controlled storage and transportation. Minor differences in physical appearance may occur due to product quantity, production conditions and residual moisture.
Physical appearance alone should not be used to confirm product identity, purity or concentration. Researchers should review the applicable batch documentation before beginning laboratory analysis.
Kvalitet och produkttransparens
Peptides Divas fokuserar på tydliga produktspecifikationer, noggrann hantering och spårbarhet på batchnivå. Tillgänglig analytisk information kan inkludera:
- Produktidentifiering
- Peptide structure
- Batch- eller lotnummer
- Rapporterad renhet
- HPLC-analys
- Masspektrometridata
- Testinformation
- Produktens utseende
- Förvaringsrekommendationer
Detta ger forskare tydlig och spårbar produktinformation för den aktuella batchen.
Lagringsinformation
Store PT-141 in its original sealed packaging under the conditions stated on the product label and applicable batch documentation.
Protect the research material from:
- Direkt solljus
- Överdriven värme
- Fukt
- Förorening
- Skadad förpackning
- Upprepade temperaturfluktuationer
- Onödig exponering för luft
Det mottagande laboratoriet ansvarar för att fastställa lämpliga rutiner för förberedelse, hantering och förvaring för sitt specifika forskningsprotokoll.
Why Choose PT-141?
PT-141 provides a distinctive cyclic molecular structure and broad melanocortin receptor research profile.
Key research advantages include:
- Tydligt definierad cyklisk heptapeptidstruktur
- Direct relevance to MC4R research
- Suitable for central melanocortin signalling studies
- Useful for MC1R and melanocyte research
- Relevant for GPCR pharmacology
- Valuable for cyclic peptide analysis
- Lämplig för struktur-aktivitetsforskning
- Praktisk frystorkad presentation
- Tydlig batchspecifik produktinformation
Varför beställa från Peptides Divas?
Peptides Divas kombinerar noggrant utvalt forskningsmaterial med snabb, pålitlig och professionell service. Kunderna drar nytta av:
- Tydligt visade produktspecifikationer
- Batchspecifik analytisk information
- Snabb orderhantering
- Säker och diskret förpackning
- Spårbara fraktalternativ
- Noggrant skydd av flaskorna
- Responsiv kundsupport
- Pålitlig europeisk leverans
Choose PT-141 from Peptides Divas for advanced laboratory research involving melanocortin receptors, central signalling, neuroendocrine pathways and cyclic peptide pharmacology.
For laboratory research use only. Not intended for human or veterinary use.
