PT-141 (Bremelanotide) – Cyclic Melanocortin Research Peptide
PT-141, also known as Bremelanotide, is an advanced synthetic cyclic heptapeptide developed for professional laboratory research involving melanocortin receptor activity, central signalling pathways and cyclic peptide pharmacology.
Its compact molecular structure and broad melanocortin receptor profile make PT-141 particularly relevant for studies involving MC4R and MC1R activity, G-protein-coupled receptor signalling, neuroendocrine communication and peptide structure–activity relationships.
PT-141 is supplied as a premium lyophilised research material in a securely sealed vial with clear batch information, professional packaging and fast order processing from Peptides Divas.
Vigtige produktfunktioner
- Syntetisk cyklisk heptapeptid
- Also known as Bremelanotide and PT141
- Advanced melanocortin receptor agonist
- Relevant for MC4R and MC1R research
- Suitable for central melanocortin signalling studies
- Useful for GPCR pharmacology
- Relevant for cyclic peptide characterisation
- Leveres som frysetørret forskningsmateriale
- Tydelige batchspecifikke produktoplysninger
- Sikker og diskret emballage
- Hurtig og sporbar levering i Europa
What Is PT-141?
PT-141 is a synthetic melanocortin peptide with a conformationally restricted cyclic structure.
The molecule belongs to the melanocortin peptide family and is structurally related to alpha-melanocyte-stimulating hormone analogues. Its cyclic design helps create a stable and clearly defined molecular profile for receptor-binding and signalling research.
PT-141 is also known by its scientific name, Bremelanotide. The two names refer to the same active peptide compound.
Alternative produktnavne
PT-141 may be identified under several names:
- PT-141
- PT141
- Bremelanotide
- Bremelanotide acetate
- Cyclic melanocortin peptide
- Melanocortin-receptoragonist
Researchers should always confirm the exact chemical form and batch specifications using the product label and applicable analytical documentation.
Molekylstruktur
Bremelanotide is a synthetic cyclic heptapeptide with an acetylated amino terminus and a free acid at the carboxyl terminus.
Its peptide structure is commonly represented as:
Ac-Nle-cyclo-(Asp–His–D-Phe–Arg–Trp–Lys–OH)
Important structural characteristics include:
- Seven-amino-acid cyclic peptide structure
- Lactam-bridged molecular design
- Acetylated amino terminus
- Free carboxyl terminus
- Modified amino-acid components
- Conformationally restricted structure
- Broad melanocortin receptor activity
- Distinct analytical profile
These characteristics make PT-141 particularly useful for cyclic peptide, receptor-binding and structure–activity research.
Melanocortin Receptor Research
PT-141 is studied as a non-selective agonist of several melanocortin receptor subtypes.
Relevant receptor systems include:
The relative activity of PT-141 differs between receptor subtypes, with MC1R and MC4R representing particularly important areas of scientific interest.
Potential research applications include:
- Melanocortin receptor binding
- Receptoraktivering
- Ligand-receptor-interaktioner
- G-proteinkoblet receptorsignalering
- Cykliske AMP-veje
- Intracellulær signaltransduktion
- Receptorinternalisering
- Receptor desensibilisering
- Koncentration-responsforhold
- Comparative receptor pharmacology
MC4R and Central Signalling Research
The melanocortin 4 receptor, known as MC4R, is expressed in multiple regions of the central nervous system.
This makes PT-141 particularly relevant for research involving:
- Central melanocortin-signalering
- Hypothalamisk receptoraktivitet
- Neuroendocrine communication
- Neural GPCR pathways
- Behaviour-related signalling models
- Autonom kommunikation
- Dopamine-associated research pathways
- Receptor-expression analysis
- Central ligand–receptor interactions
- Comparative MC4R agonist studies
PT-141 is frequently used as a research reference for examining how melanocortin receptor activation may influence centrally mediated signalling.
MC1R and Melanocyte Research
MC1R is strongly associated with melanocyte biology and pigmentation-related signalling.
PT-141 may therefore also be relevant for laboratory research involving:
- MC1R-receptoraktivering
- Melanocytsignalering
- Melanin-expression pathways
- Pigmenteringsrelaterede cellulære modeller
- Receptorselektivitet
- Comparative melanocortin ligands
- Cellular concentration responses
- Melanocyte gene expression
- GPCR signalling in pigment cells
- Receptor-mediated cellular communication
These applications describe laboratory research pathways and do not represent cosmetic claims.
Neuroendocrine Research
Melanocortin receptors contribute to communication between the central nervous system and endocrine pathways.
Potential PT-141 research areas include:
- Neuroendokrin signalering
- Hypothalamic pathway research
- Central receptor activation
- Neural transmitter interactions
- Hormone-associated signalling
- Behavioural response models
- Autonomic nervous system research
- Receptor-mediated cellular communication
- Comparative neuropeptide pharmacology
- Central nervous system peptide research
Experimental results can differ depending on the receptor subtype, cell type, concentration, administration model and analytical method.
Cyclic Peptide Research
The conformationally restricted structure of PT-141 makes it especially relevant for peptide design and molecular engineering.
Potential research topics include:
- Peptidcyklisering
- Lactam bridge formation
- Konformationsbegrænsning
- Molekylær stabilitet
- Enzymatic degradation
- Optimering af receptorbinding
- Modificeret aminosyreanalyse
- Peptide pharmacology
- Struktur-aktivitetsforhold
- Comparative linear and cyclic peptides
- Molekylær modellering
- Synthetic peptide chemistry
Researchers may compare PT-141 with Melanotan II, alpha-MSH or other melanocortin ligands to examine how small structural differences influence receptor activity.
PT-141 Versus Melanotan II
PT-141 and Melanotan II are closely related cyclic melanocortin peptides, but they should not be treated as identical compounds.
| Karakteristisk |
PT-141 |
| Scientific name |
Bremelanotide |
| Peptidtype |
Cyklisk heptapeptid |
| C-terminal structure |
Free carboxylic acid |
| Main research profile |
Central melanocortin and receptor signalling |
| Important receptor targets |
MC4R and MC1R |
| Product identity |
Distinct from Melanotan II |
Researchers should always verify the exact compound identity before beginning laboratory analysis.
Potentielle forskningsanvendelser
PT-141 may be relevant for controlled scientific research involving:
- Melanocortinreceptorens farmakologi
- MC4R receptor signalling
- MC1R receptor activity
- Central nervous system pathways
- Neuroendocrine communication
- GPCR-aktivering
- Cyklisk AMP-signalering
- Ligand-receptor-interaktioner
- Receptorselektivitet
- Receptorinternalisering
- Peptidcyklisering
- Struktur-aktivitetsforhold
- Comparative melanocortin research
- Analytisk peptidkarakterisering
- Kromatografisk analyse
- Massespektrometrianalyse
- Stabilitets- og nedbrydningstest
The exact experimental concentrations, controls and analytical procedures should be established by the qualified laboratory conducting the research.
Analytisk forskning
PT-141 may be suitable for professional laboratory analysis involving:
- Højtydende væskekromatografi
- Væskekromatografi-massespektrometri
- Bekræftelse af peptididentitet
- Molecular structure analysis
- Renhedsvurdering
- Stabilitetstestning
- Nedbrydningsprofilering
- Opløselighedsvurdering
- Sammenligning af referencematerialer
- Receptor-binding assays
- Formuleringskompatibilitet
- Udvikling af analytiske metoder
Product identity and analytical quality should always be evaluated using documentation associated with the applicable batch.
Produktspecifikationer
| Produktkarakteristik |
Information |
| Produktnavn |
PT-141 |
| Scientific name |
Bremelanotide |
| Alternative form |
Bremelanotide acetate |
| Produktkategori |
Syntetisk forskningspeptid |
| Forbindelsestype |
Cyclic melanocortin receptor agonist |
| Peptide structure |
Cyklisk heptapeptid |
| Important research targets |
MC4R and MC1R |
| Primary research areas |
Melanocortin and neuroendocrine signalling |
| Form |
Frysetørret forskningsmateriale |
| Præsentation |
Sikkert forseglet forskningsflaske |
| Dokumentation |
Batchspecifikke analytiske oplysninger |
| Emballage |
Sikker og diskret emballage |
| Tilsigtet anvendelse |
Videnskabelig, analytisk og laboratorieforskning |
Frysetørret forskningsformat
PT-141 is supplied as a lyophilised research material in a securely sealed vial.
Lyophilisation removes moisture and helps support peptide stability during controlled storage and transportation. Minor differences in physical appearance may occur due to product quantity, production conditions and residual moisture.
Physical appearance alone should not be used to confirm product identity, purity or concentration. Researchers should review the applicable batch documentation before beginning laboratory analysis.
Kvalitet og produkttransparens
Peptides Divas focuses on clear product specifications, careful handling and batch-level traceability.
Available analytical information may include:
- Produktidentifikation
- Peptide structure
- Batch- eller lotnummer
- Rapporteret renhed
- HPLC-analyse
- Massespektrometridata
- Testoplysninger
- Produktets udseende
- Opbevaringsanbefalinger
This provides researchers with clear and traceable product information for the applicable batch.
Opbevaringsoplysninger
Store PT-141 in its original sealed packaging under the conditions stated on the product label and applicable batch documentation.
Protect the research material from:
- Direkte sollys
- Overdreven varme
- Fugtighed
- Forurening
- Beskadiget emballage
- Gentagne temperaturudsving
- Unødvendig eksponering for luft
The receiving laboratory is responsible for establishing appropriate preparation, handling and storage procedures for its specific research protocol.
Why Choose PT-141?
PT-141 provides a distinctive cyclic molecular structure and broad melanocortin receptor research profile.
Key research advantages include:
- Klart defineret cyklisk heptapeptidstruktur
- Direct relevance to MC4R research
- Suitable for central melanocortin signalling studies
- Useful for MC1R and melanocyte research
- Relevant for GPCR pharmacology
- Valuable for cyclic peptide analysis
- Suitable for structure–activity research
- Praktisk frysetørret præsentation
- Tydelige batchspecifikke produktoplysninger
Hvorfor bestille fra Peptides Divas?
Peptides Divas combines carefully selected research materials with fast, reliable and professional service.
Customers benefit from:
- Tydelig viste produktspecifikationer
- Batchspecifikke analytiske oplysninger
- Hurtig ordrebehandling
- Sikker og diskret emballage
- Sporbare forsendelsesmuligheder
- Omhyggelig beskyttelse af hætteglasset
- Responsiv kundesupport
- Pålidelig europæisk levering
Choose PT-141 from Peptides Divas for advanced laboratory research involving melanocortin receptors, central signalling, neuroendocrine pathways and cyclic peptide pharmacology.
For laboratory research use only. Not intended for human or veterinary use.
